eIF4A3-IN-18
Modify Date: 2024-04-03 09:39:31
eIF4A3-IN-18 structure
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Common Name | eIF4A3-IN-18 | ||
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| CAS Number | 1402931-84-3 | Molecular Weight | 500.54 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H28N2O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of eIF4A3-IN-18eIF4A3-IN-18 (compound 74) is a silvestrol (HY-13251) analogue. eIF4A3-IN-18 interferes the assembling of eIF4F translation complex with EC50 values of 0.8, 35 and 2 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-18 also has cytotoxicity to RMPI-8226 cells with an LC50 of 0.06 nM. eIF4A3-IN-18 can be used for the research of human cancer pathogenesis[1]. |
| Name | eIF4A3-IN-18 |
|---|
| Description | eIF4A3-IN-18 (compound 74) is a silvestrol (HY-13251) analogue. eIF4A3-IN-18 interferes the assembling of eIF4F translation complex with EC50 values of 0.8, 35 and 2 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-18 also has cytotoxicity to RMPI-8226 cells with an LC50 of 0.06 nM. eIF4A3-IN-18 can be used for the research of human cancer pathogenesis[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C29H28N2O6 |
|---|---|
| Molecular Weight | 500.54 |