Dual AChE-MAO B-IN-2

Modify Date: 2025-08-27 19:23:36

Dual AChE-MAO B-IN-2 Structure
Dual AChE-MAO B-IN-2 structure
Common Name Dual AChE-MAO B-IN-2
CAS Number 1801157-64-1 Molecular Weight 415.48
Density N/A Boiling Point N/A
Molecular Formula C26H25NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dual AChE-MAO B-IN-2


Dual AChE-MAO B-IN-2 is a potent AChE and MAO B dual inhibitor with IC50s of 0.12 µM and 0.01 µM for b>AChE and MAO B, respectively. Dual AChE-MAO B-IN-2 has the potential for the research of Alzheimer’s disease[1].

 Names

Name Dual AChE-MAO B-IN-2

 Dual AChE-MAO B-IN-2 Biological Activity

Description Dual AChE-MAO B-IN-2 is a potent AChE and MAO B dual inhibitor with IC50s of 0.12 µM and 0.01 µM for b>AChE and MAO B, respectively. Dual AChE-MAO B-IN-2 has the potential for the research of Alzheimer’s disease[1].
Related Catalog
Target

MAO-B:4.5 μM (Ki)

In Vitro Dual AChE-MAO B-IN-2 (compound 1) shows a +5.5 °C increase in the MAO B enzyme Tm value[1].
References

[1]. Ekström F, et al. Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures. ACS Med Chem Lett. 2022, 13(3):499-506.

 Chemical & Physical Properties

Molecular Formula C26H25NO4
Molecular Weight 415.48
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