eIF4A3-IN-10

Modify Date: 2025-11-25 17:38:43

eIF4A3-IN-10 structure	Common Name	eIF4A3-IN-10
	CAS Number	1402931-72-9	Molecular Weight	519.54
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₉NO₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of eIF4A3-IN-10

eIF4A3-IN-10 (compound 58) is a silvestrol (HY-13251) analogue. eIF4A3-IN-10 interferes the assembling of eIF4F translation complex with EC50s of 35 and 100 nM for myc-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-10 can be used for the research of human cancer pathogenesis[1].

Name	eIF4A3-IN-10

Description	eIF4A3-IN-10 (compound 58) is a silvestrol (HY-13251) analogue. eIF4A3-IN-10 interferes the assembling of eIF4F translation complex with EC50s of 35 and 100 nM for myc-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-10 can be used for the research of human cancer pathogenesis[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Eukaryotic Initiation Factor (eIF)
References	[1]. Liu T, et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J Med Chem. 2012 Oct 25;55(20):8859-78.

Molecular Formula	C₂₉H₂₉NO₈
Molecular Weight	519.54
InChIKey	QGBWLAVVBBEGCQ-VBIJGHLJSA-N
SMILES	CNC(=O)c1cc(OC)c2c(c1)OC1(c3ccc(OC)cc3)C(c3ccccc3)C(C(=O)OC)C(O)C21O

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eIF4A3-IN-10

Use of eIF4A3-IN-10

Names

eIF4A3-IN-10 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.