5'-Guanylic acid

Names

[ CAS No. ]:
85-32-5

[ Name ]:
5'-Guanylic acid

[Synonym ]:
5 -GUANOSINEMONOPHOSPHATE
GUANIDINE PHOSPHATE, MONOBASIC
Guanine 5'-Monophosphate
GUANOSINE-5'-MONOPHOSPHATE NA
disodium (5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
2-Imino-9-(5-O-phosphono-β-D-ribofuranosyl)-3,9-dihydro-2H-purin-6-ol
GUANYLIC ACID
2H-purin-6-ol, 3,9-dihydro-2-imino-9-(5-O-phosphono-β-D-ribofuranosyl)-
GUANOSINE-5'-MONOPHOSPHONATE
GUANOSINE-5'-MONOPHOSPHATE FREE ACID
guanylate
guanosine 5′-monophosphate
EINECS 201-598-8
guanosine-5′-monophosphate
9H-purin-6-ol, 2-amino-9-(5-O-phosphono-β-D-ribofuranosyl)-
Guo-5'-P
2-amino-9-(5-O-phosphono-β-D-ribofuranosyl)-9H-purin-6-ol
GMP
Guanosine 5'-monophosphate
guanosine 5'-phosphate
GUANOSINE 5'-MONOPHOSPHORIC ACID
5'-inosine monophosphate
[(2R,3S,4R,5R)-5-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furanyl]methyl dihydrogen phosphate
5'-GUANOSINE MONOPHOSPHATE
5′-Guanylic acid
5-GUANOSINE MONOPHOSPHATE
GUANOSINE MONOPHOSPHATE
Guanylic Aicd
GUANILICACID
MFCD00057066
Guanosine-5'-monophosphate
5'-Guanylic acid
GUANOSINE-5'-MONOPHOSPHORIC ACID
GUANILLICACID

Biological Activity

[Description]:

Guanylic acid is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.

[Related Catalog]:

Research Areas >> Metabolic Disease

Natural Products >> Acids and Aldehydes

[Target]

Human Endogenous Metabolite

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
2.5±0.1 g/cm3

[ Boiling Point ]:
872.4±75.0 °C at 760 mmHg

[ Melting Point ]:
91 - 93ºC

[ Molecular Formula ]:
C₁₀H₁₄N₅O₈P

[ Molecular Weight ]:
363.221

[ Flash Point ]:
481.4±37.1 °C

[ Exact Mass ]:
363.057983

[ PSA ]:
215.85000

[ LogP ]:
-1.97

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.946

[ Storage condition ]:
Store at 0-5°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MF9283000

CHEMICAL NAME :: 5'-Guanylic acid

CAS REGISTRY NUMBER :: 85-32-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H14-N5-O8-P

MOLECULAR WEIGHT :: 363.26

WISWESSER LINE NOTATION :: T56 BN DN FN HNVJ GZ D- BT5OTJ CQ DQ E1OPOQQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Human Cells - not otherwise specified

DOSE/DURATION :: 1 mmol/L

REFERENCE :: JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- Volume(issue)/page/year: 65,52,1975

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36/37

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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