5'-GTP (trisodium salt)

Names

[ Name ]:
5'-GTP (trisodium salt)

[Synonym ]:
trisodium,[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate
GTP,Trisodium Salt
Trisodium 5'-O-(hydroxy{[(phosphonatooxy)phosphinato]oxy}phosphoryl)guanosine
Guanosine 5'-triphosphate disodium salt
MFCD00084663
Guanosine, 5'-(tetrahydrogen triphosphate), sodium salt (1:3)
5'-GTP-Na2
EINECS 252-847-2
5'-GTP (trisodium salt)

Biological Activity

[Description]:

5'-GTP trisodium salt is an activator of the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Others

[Related Small Molecules]

Chemical & Physical Properties

[ Boiling Point ]:
1028.3ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₆N₅Na₃O₁₄P₃

[ Molecular Weight ]:
592.15

[ Flash Point ]:
575.7ºC

[ PSA ]:
337.02000

[ Storage condition ]:
−70°C

[ Water Solubility ]:
H2O: 50 mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
23/24/25-36/37/38-39/23/24/25

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Osmoregulatory bicarbonate secretion exploits H(+)-sensitive haemoglobins to autoregulate intestinal O2 delivery in euryhaline teleosts.

J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. 184(7) , 865-76, (2014)

Marine teleost fish secrete bicarbonate (HCO3 (-)) into the intestine to aid osmoregulation and limit Ca(2+) uptake by carbonate precipitation. Intestinal HCO3 (-) secretion is associated with an equi...

Cell-free expression and in meso crystallisation of an integral membrane kinase for structure determination.

Cell. Mol. Life Sci. 71(24) , 4895-910, (2014)

Membrane proteins are key elements in cell physiology and drug targeting, but getting a high-resolution structure by crystallographic means is still enormously challenging. Novel strategies are in big...

A potentially novel nicotinic receptor in Aplysia neuroendocrine cells.

J. Neurophysiol. 112(2) , 446-62, (2014)

Nicotinic receptors form a diverse group of ligand-gated ionotropic receptors with roles in both synaptic transmission and the control of excitability. In the bag cell neurons of Aplysia, acetylcholin...