2',3'-O-Isopropylideneguanosine
Names
[ CAS No. ]:
362-76-5
[ Name ]:
2',3'-O-Isopropylideneguanosine
[Synonym ]:
2',3'-O-Isopropylidene-D-guanosine
9-[(3aR,4R,6R,6aR)-4-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-2-azanyl-3H-purin-6-one
9-(2,3-O-Isopropylidene-β-D-ribofuranosyl)guanine
2-amino-9-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-1H-purin-6(9H)-one
2',3'-O-Isopropylideneguanosine
2',3'-O-ISOPROPYLIDENE-GUANOSINE
9-[(3aR,4R,6R,6aR)-4-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-2-amino-3H-purin-6-one
2',3'-O-(1-methylethylidene)-guanosine
2',3'-O-Isopropylide
EINECS 206-651-9
2-amino-9-[(3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-1,9-dihydro-6H-purin-6-one
2',3'-ISOPROPYLIDENE-GUANOSINE
2′,3′-O-Isopropylideneguanosine
Guanosine, 2',3'-O-(1-methylethylidene)-
9-[(3aR,4R,6R,6aR)-2,2-dimethyl-4-methylol-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-2-amino-3H-purin-6-one
2',3'-IPG
MFCD00057081
Chemical & Physical Properties
[ Density]:
1.9±0.1 g/cm3
[ Boiling Point ]:
647ºC at 760mmHg
[ Melting Point ]:
296 °C
[ Molecular Formula ]:
C13H17N5O5
[ Molecular Weight ]:
323.305
[ Flash Point ]:
345.1ºC
[ Exact Mass ]:
323.122955
[ PSA ]:
137.51000
[ LogP ]:
0.85
[ Index of Refraction ]:
1.828
[ Storage condition ]:
-20°C Freezer
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Precursor & DownStream
Precursor
DownStream
Articles
IARC Sci. Publ. 70 , 413-418, (1986)
Mutagens present in crude samples such as heated glucose can be detected or identified by means of the adducts formed upon reaction with a fluorescent guanosine derivative (FG) or isopropylideneguanos...
Hydroxylation of guanine in nucleosides and DNA at the C-8 position by heated glucose and oxygen radical-forming agents.Environ. Health Perspect. 67 , 111-116, (1986)
Heated glucose is mutagenic to Salmonella typhimurium TA 100 in the absence of S-9 mix. For identifying unknown mutagens in heated glucose (dry solid, 200 degrees C, 20 min), reaction with isopropylid...
Synthesis and application of a new 2',3'-isopropylidene guanosine substituted cap analog.Bioorg. Med. Chem. Lett. 18 , 4828-4832, (2008)
The synthesis and biological evaluation of a new cap analog, which is modified at the C2' and C3' positions of N(7)-methylguanosine is reported. The new cap analog, P(1)-2',3'-isopropylidene, 7-methyl...