5'-Guanylic acid

Modify Date: 2024-01-02 20:12:48

5'-Guanylic acid Structure
5'-Guanylic acid structure
Common Name 5'-Guanylic acid
CAS Number 85-32-5 Molecular Weight 363.221
Density 2.5±0.1 g/cm3 Boiling Point 872.4±75.0 °C at 760 mmHg
Molecular Formula C10H14N5O8P Melting Point 91 - 93ºC
MSDS N/A Flash Point 481.4±37.1 °C

 Use of 5'-Guanylic acid


Guanylic acid is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.

 Names

Name gmp
Synonym More Synonyms

 5'-Guanylic acid Biological Activity

Description Guanylic acid is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
Related Catalog
Target

Human Endogenous Metabolite

 Chemical & Physical Properties

Density 2.5±0.1 g/cm3
Boiling Point 872.4±75.0 °C at 760 mmHg
Melting Point 91 - 93ºC
Molecular Formula C10H14N5O8P
Molecular Weight 363.221
Flash Point 481.4±37.1 °C
Exact Mass 363.057983
PSA 215.85000
LogP -1.97
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.946
Storage condition Store at 0-5°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MF9283000
CHEMICAL NAME :
5'-Guanylic acid
CAS REGISTRY NUMBER :
85-32-5
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C10-H14-N5-O8-P
MOLECULAR WEIGHT :
363.26
WISWESSER LINE NOTATION :
T56 BN DN FN HNVJ GZ D- BT5OTJ CQ DQ E1OPOQQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Human Cells - not otherwise specified
DOSE/DURATION :
1 mmol/L
REFERENCE :
JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- Volume(issue)/page/year: 65,52,1975

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases S26-S36/37
WGK Germany 3

 Synthetic Route

 Synonyms

5 -GUANOSINEMONOPHOSPHATE
GUANIDINE PHOSPHATE, MONOBASIC
Guanine 5'-Monophosphate
GUANOSINE-5'-MONOPHOSPHATE NA
disodium (5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
2-Imino-9-(5-O-phosphono-β-D-ribofuranosyl)-3,9-dihydro-2H-purin-6-ol
GUANYLIC ACID
2H-purin-6-ol, 3,9-dihydro-2-imino-9-(5-O-phosphono-β-D-ribofuranosyl)-
GUANOSINE-5'-MONOPHOSPHONATE
GUANOSINE-5'-MONOPHOSPHATE FREE ACID
guanylate
guanosine 5′-monophosphate
EINECS 201-598-8
guanosine-5′-monophosphate
9H-purin-6-ol, 2-amino-9-(5-O-phosphono-β-D-ribofuranosyl)-
Guo-5'-P
2-amino-9-(5-O-phosphono-β-D-ribofuranosyl)-9H-purin-6-ol
GMP
Guanosine 5'-monophosphate
guanosine 5'-phosphate
GUANOSINE 5'-MONOPHOSPHORIC ACID
5'-inosine monophosphate
[(2R,3S,4R,5R)-5-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furanyl]methyl dihydrogen phosphate
5'-GUANOSINE MONOPHOSPHATE
5′-Guanylic acid
5-GUANOSINE MONOPHOSPHATE
GUANOSINE MONOPHOSPHATE
Guanylic Aicd
GUANILICACID
MFCD00057066
Guanosine-5'-monophosphate
5'-Guanylic acid
GUANOSINE-5'-MONOPHOSPHORIC ACID
GUANILLICACID
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