D-Ribose

Modify Date: 2024-01-02 18:30:17

D-Ribose Structure
D-Ribose structure
Common Name D-Ribose
CAS Number 50-69-1 Molecular Weight 150.13
Density 1.5±0.1 g/cm3 Boiling Point 415.5±38.0 °C at 760 mmHg
Molecular Formula C5H10O5 Melting Point 88-92ºC
MSDS Chinese USA Flash Point 219.2±23.3 °C

 Use of D-Ribose


D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].

 Names

Name aldehydo-D-ribose
Synonym More Synonyms

 D-Ribose Biological Activity

Description D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].
Related Catalog
In Vitro D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism[1]. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].
References

[1]. Hong J, et al. D-ribose induces nephropathy through RAGE-dependent NF-κB inflammation. Arch Pharm Res. 2018 Aug;41(8):838-847.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 415.5±38.0 °C at 760 mmHg
Melting Point 88-92ºC
Molecular Formula C5H10O5
Molecular Weight 150.13
Flash Point 219.2±23.3 °C
Exact Mass 150.052826
PSA 97.99000
LogP -2.39
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.544

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VJ2275000
CHEMICAL NAME :
Ribose, D-
CAS REGISTRY NUMBER :
50-69-1
BEILSTEIN REFERENCE NO. :
1723081
LAST UPDATED :
199801
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C5-H10-O5
MOLECULAR WEIGHT :
150.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intrauterine
DOSE :
5045 ug/kg
SEX/DURATION :
female 2 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
30 mmol/L
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 180,246,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1001 No. of Facilities: 439 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 4169 (estimated) No. of Female Employees: 2111 (estimated)

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes F
Risk Phrases R36/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS VJ2275000
HS Code 2940000000

 Synthetic Route

 Customs

HS Code 2912491000
Summary 2912491000. other aldehyde-alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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 Synonyms

RIBOSE,D-(-)
FEMA 3793
EINECS 200-059-4
D-RIB
(2R,3R,4R)-2,3,4,5-Tetrahydroxypentanal
D-Ribose
d-ribos
D-(-)-RIBOSE
Ribose (300 mg)
R-RIBOSE
D-(−)-Ribose
ribose,pure
MFCD00135453
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