2-Oxobutyric acid

Names

[ CAS No. ]:
600-18-0

[ Name ]:
2-Oxobutyric acid

[Synonym ]:
Butanoic acid, 2-oxo-
EINECS 209-986-9
α-oxobutyric acid
2-oxo-Butyric acid
a-keto-n-butyric acid
MFCD00004164
methyl-Pyruvic acid
propionyl- Formic acid
a-Oxobutyric acid
2-Oxobutyric acid
a-oxo-n-butyric acid
2-Oxobutanoic acid
a-ketobutyric acid

Biological Activity

[Description]:

2-Oxobutanoic acid is a product in the enzymatic cleavage of cystathionine.

[Related Catalog]:

Natural Products >> Acids and Aldehydes

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[In Vitro]

2-Oxobutanoic acid (alpha-Ketobutyric acid) is a product in the enzymatic cleavage of cystathionine. 2-Oxobutanoic acid is a substance that is involved in the metabolism of many amino acids as well as propanoate metabolism and C-5 branched dibasic acid metabolism. 2-Oxobutanoic acid is also one of the degradation products of threonine. It can be converted into propionyl-CoA (and subsequently methylmalonyl CoA, which can be converted into succinyl CoA, a citric acid cycle intermediate), and thus enter the citric acid cycle[1].

[References]

[1]. CARROLL WR, et al. alpha-Ketobutyric acid as a product in the enzymatic cleavage of cystathionine. J Biol Chem. 1949 Aug;180(1):375-82.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
177.8±0.0 °C at 760 mmHg

[ Melting Point ]:
30-34 °C(lit.)

[ Molecular Formula ]:
C₄H₆O₃

[ Molecular Weight ]:
102.089

[ Flash Point ]:
65.0±15.2 °C

[ Exact Mass ]:
102.031693

[ PSA ]:
54.37000

[ LogP ]:
-0.71

[ Vapour Pressure ]:
0.5±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.427

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
1759

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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