(R)-2-HYDROXYBUTYRIC ACID

Names

[ CAS No. ]:
20016-85-7

[ Name ]:
(R)-2-HYDROXYBUTYRIC ACID

[Synonym ]:
(R)-2-Hydroxybutyric acid
MFCD01318570
(R)-2-hydroxylbutanoic acid
(R)-(+)-2-Hydroxybutanoic acid
D-2-hydroxybutyric acid
(R)-hydroxybutyric acid

Biological Activity

[Description]:

(R)-2-Hydroxybutanoic acid is the inactive isomer of 2-Hydroxybutyric acid (HY-113381), and can be used as an experimental control. 2-Hydroxybutyric acid (α-Hydroxybutyric acid ) is converted from 2-Aminobutyric acid, with 2-oxobutyric acid as an intermediate metabolite[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Landaas S, et al. The formation of 2-hydroxybutyric acid in experimental animals. Clin Chim Acta. 1975 Jan 6;58(1):23-32.

Chemical & Physical Properties

[ Density]:
1.195g/cm3

[ Boiling Point ]:
238.3ºC at 760 mmHg

[ Melting Point ]:
50-54ºC

[ Molecular Formula ]:
C₄H₈O₃

[ Molecular Weight ]:
104.10

[ Flash Point ]:
112.2ºC

[ Exact Mass ]:
104.04700

[ PSA ]:
57.53000

[ Vapour Pressure ]:
0.00759mmHg at 25°C

[ Index of Refraction ]:
1.455

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
37/38-41

[ Safety Phrases ]:
26-39

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2918199090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

(1)H NMR-based metabonomic investigation of the effect of two different exercise sessions on the metabolic fingerprint of human urine.

J. Proteome Res. 9(12) , 6405-16, (2010)

Physical exercise modifies animal metabolism profoundly. Until recently, biochemical investigations related to exercise focused on a small number of biomolecules. In the present study, we used a holis...

Kinetic resolution of 2-hydroxybutanoate racemic mixtures by NAD-independent L-lactate dehydrogenase.

Bioresour. Technol. 102(7) , 4595-9, (2011)

Optically active D-2-hydroxybutanoate is an important building block intermediate for medicines and biodegradable poly(2-hydroxybutanoate). Kinetic resolution of racemic 2-hydroxybutanoate may be a gr...

Metabolic characterisation of plasma in juveniles with glycogen storage disease type 1a (GSD1a) by high-resolution (1)H NMR spectroscopy.

NMR Biomed. 20(4) , 401-12, (2007)

This paper reports the first application of high-resolution (1)H NMR spectroscopy to the plasma of five juveniles with glycogen storage disease type 1a (GSD1a), permitting the characterisation of the ...