Estriol 3-β-D-Glucuronide (sodium salt)

Estriol 3-β-D-Glucuronide (sodium salt) Structure
Estriol 3-β-D-Glucuronide (sodium salt) structure
Common Name Estriol 3-β-D-Glucuronide (sodium salt)
CAS Number 15087-06-6 Molecular Weight 487.49500
Density N/A Boiling Point N/A
Molecular Formula C24H32NaO9 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS08
GHS08
Signal Word Warning

Klotho is a novel beta-glucuronidase capable of hydrolyzing steroid beta-glucuronides.

J. Biol. Chem. 279(11) , 9777-84, (2004)

klotho mutant mice provide a unique model to analyze mechanisms of aging because their phenotypes resemble those of human aging-associated disorders. The klotho gene encodes Klotho, a type I membrane protein that shares sequence similarity with members of the...

Urinary estrone conjugate and pregnanediol 3-glucuronide enzyme immunoassays for population research.

Clin. Chem. 49(7) , 1139-48, (2003)

Monitoring of reproductive steroid hormones at the population level requires frequent measurements, hormones or metabolites that remain stable under less than ideal collection and storage conditions, a long-term supply of antibodies, and assays useful for a r...

Estriol and its conjugates in late pregnancy determined by extraction with Carbopack B and liquid chromatography with fluorometric detection.

Clin. Chem. 31(10) , 1698-702, (1985)

We report a method for measuring estriol and its intact conjugates in urine, serum, and amniotic fluid. A single assay can be done within about 50 min, eight samples assayed in less than 5 h. A 70-microL urine sample is diluted and the estriol conjugates are ...

Direct determination of estriol 3- and 16-glucuronides in pregnancy urine by column-switching liquid chromatography with electrospray tandem mass spectrometry.

Biomed. Chromatogr. 17(4) , 219-25, (2003)

Using column-switching liquid chromatography/tandem mass spectrometry (LC-MS/MS), we developed an improved analytical method of urinary estriol glucuronides. This new method is derived predominantly from maternal and fetal precursors in pregnancy. We used in ...

Direct determination of estriol conjugates in amniotic fluid by capillary electrophoresis with electrospray tandem mass spectrometry.

Rapid Commun. Mass Spectrom. 20(19) , 2995-8, (2006)

The metabolism of estriol-3-glucosiduronate and estriol in the rabbit.

Endocrinol. Jpn. 27(2) , 175-82, (1980)

Urinary metabolites of [6,7-3H]-estriol-3-glucosiduronate and of [6, 7-3H]-estriol in intact female rabbits were analyzed. The separation of urinary metabolites was performed by countercurrent distribution followed by DEAE-Sephadex A-25 column chromatography....

Direct radioimmunoassay of urinary estrogen and pregnanediol glucuronides during the menstrual cycle.

Am. J. Obstet. Gynecol. 137(4) , 443-50, (1980)

Antigenic properties of estriol 3-glucuronide-[C-6]-bovine serum albumin conjugates having oxime bridges.

J. Pharmacobiodyn. 6(9) , 692-7, (1983)

The preparation and antigenic properties of estriol 3-glucuronide-bovine serum albumin (BSA) conjugate in which the hapten is linked to the carrier protein through an (O-3-carboxypropylcarbamoylmethyl)oxime bridge at the C-6 position on the steroid nucleus, h...

Plasma estriol and its conjugates following oral and vaginal administration of estriol to postmenopausal women: correlations with gonadotropin levels.

Am. J. Obstet. Gynecol. 138(8) , 1137-41, (1980)

A study was designed to compared the metabolic fate and the biologic effects of 4 mg of estriol (E3) administered either orally or vaginally to six postmenopausal women. Blood samples were collected every hour for 6 hours and five different estriol fractions ...

Deuterium labelled steroid hormones: syntheses and application in quantitation and endocrinology.

J. Steroid Biochem. 14(8) , 793-800, (1981)

Methods for the syntheses of various multi-deuterated steroid hormones have been summarized and evaluated. Applications of these latter compounds in combination with the technique of gas chromatography/mass spectrometry are described in the general areas of q...