Nimustine HCL
Nimustine HCL structure
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Common Name | Nimustine HCL | ||
|---|---|---|---|---|
| CAS Number | 55661-38-6 | Molecular Weight | 309.152 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H14Cl2N6O2 | Melting Point | 186 °C | |
| MSDS | USA | Flash Point | N/A | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Two new triterpenoid saponins from the aerial parts of Anemone taipaiensis.
J. Asian Nat. Prod. Res. 17 , 576-85, (2015) Phytochemical study on the aerial parts of Anemone taipaiensis for the first time led to the isolation of two new oleanane-type triterpenoid saponins 1 and 2, together with four known saponins (3-6). Their structures were elucidated by extensive spectroscopic... |
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Evaluation of the drug sensitivity and expression of 16 drug resistance-related genes in canine histiocytic sarcoma cell lines.
J. Vet. Med. Sci. 77 , 677-84, (2015) Canine histiocytic sarcoma (HS) is an aggressive tumor type originating from histiocytic cell lineages. This disease is characterized by poor response to chemotherapy and short survival time. Therefore, it is of critical importance to identify and develop eff... |
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A high-throughput pharmaceutical screen identifies compounds with specific toxicity against BRCA2-deficient tumors.
Clin. Cancer Res. 16(1) , 99-108, (2010) Hereditary breast cancer is partly explained by germline mutations in BRCA1 and BRCA2. Although patients carry heterozygous mutations, their tumors have typically lost the remaining wild-type allele. Selectively targeting BRCA deficiency may therefore constit... |
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Increased susceptibility to chemotherapeutic alkylating agents of mice deficient in DNA repair methyltransferase.
Carcinogenesis 21 , 1879, (2000) O(6)-methylguanine-DNA methyltransferase plays vital roles in preventing induction of mutations and cancer as well as cell death related to alkylating agents. Mice defective in the MGMT: gene, encoding the methyltransferase, were used to evaluate cell death-i... |