Journal of Asian Natural Products Research 2015-05-01

Two new triterpenoid saponins from the aerial parts of Anemone taipaiensis.

Hui Li, Xiao-Yang Wang, Xia-Yin Wang, Dong Hua, Yang Liu, Hai-Feng Tang

Index: J. Asian Nat. Prod. Res. 17 , 576-85, (2015)

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Abstract

Phytochemical study on the aerial parts of Anemone taipaiensis for the first time led to the isolation of two new oleanane-type triterpenoid saponins 1 and 2, together with four known saponins (3-6). Their structures were elucidated by extensive spectroscopic analysis and chemical evidences. Saponins 2-4 exhibited cytotoxicity against human glioblastoma U251MG cell line with IC50 values ranging from 1.56 to 80.62 μM.