Fitoterapia 2015-04-01

Five new diarylheptanoids from the rhizomes of Curcuma kwangsiensis and their antiproliferative activity.

Shao-Dan Chen, Jin-Tao Gao, Jing-Gong Liu, Bo Liu, Rui-Zhi Zhao, Chuan-Jian Lu

Index: Fitoterapia 102 , 67-73, (2015)

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Abstract

Five new diarylheptanoids (1-5), along with nine known ones (6-14), were isolated from the rhizomes of Curcuma kwangsiensis. Their structures were established on the basis of spectroscopic analyses. Compounds 1-3 were cyclic diarylheptanoids rarely discovered from C. kwangsiensis. Of all the isolated compounds, compound 4 showed moderate antiproliferative activity on HH and HaCaT cells.Copyright © 2015. Published by Elsevier B.V.