Glycopyrrolate
Glycopyrrolate structure
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Common Name | Glycopyrrolate | ||
|---|---|---|---|---|
| CAS Number | 596-51-0 | Molecular Weight | 398.335 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H28BrNO3 | Melting Point | 193 - 194.5ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Distribution and density of contacts from noradrenergic and serotonergic boutons on the dendrites of neck flexor motoneurons in the adult cat.
J. Comp. Neurol. 523 , 1701-16, (2015) Serotonergic (5-HT) and noradrenergic (NA) input to spinal motoneurons is essential for generating plateau potentials and self-sustained discharges. Extensor motoneurons are densely innervated by 5-HT and NA synapses and have robust plateau potentials and sel... |
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Low birth weight male guinea pig offspring display increased visceral adiposity in early adulthood.
PLoS ONE 9(6) , e98433, (2014) Uteroplacental insufficiency (UPI)-induced intrauterine growth restriction (IUGR) predisposes individuals to adult visceral obesity. We postulated that low birth weight (LBW) offspring, from UPI-induced IUGR pregnancies, would display a visceral adipose lipog... |
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Assessment of sensorimotor gating following selective lesions of cholinergic pedunculopontine neurons.
Eur. J. Neurosci. 40(10) , 3526-37, (2014) Sensorimotor gating is the state-dependent transfer of sensory information into a motor system. When this occurs at an early stage of the processing stream it enables stimuli to be filtered out or partially ignored, thereby reducing the demands placed on adva... |
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Deficits in motor performance after pedunculopontine lesions in rats--impairment depends on demands of task.
Eur. J. Neurosci. 40(8) , 3224-36, (2014) Anatomically and functionally located between basal ganglia and brainstem circuitry, the pedunculopontine tegmental nucleus (PPTg) is in a pivotal position to contribute to motor behavior. Studies in primates have reported akinesia and postural instability fo... |
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[Glycopyrrolate, an alternative to deptropine citratie when treating sialorrhea].
J. Pharm. Belg. (1) , 22-3, (2010)
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Acute Phase Proteins in Cerebrospinal Fluid from Dogs with Naturally-Occurring Spinal Cord Injury.
J. Neurotrauma 32 , 1658-65, (2015) Spinal cord injury (SCI) affects thousands of people each year and there are no treatments that dramatically improve clinical outcome. Canine intervertebral disc herniation is a naturally-occurring SCI that has similarities to human injury and can be used as ... |
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Patient-specific Immune States before Surgery Are Strong Correlates of Surgical Recovery.
Anesthesiology 123 , 1241-55, (2015) Recovery after surgery is highly variable. Risk-stratifying patients based on their predicted recovery profile will afford individualized perioperative management strategies. Recently, application of mass cytometry in patients undergoing hip arthroplasty reve... |
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An in vivo zebrafish screen identifies organophosphate antidotes with diverse mechanisms of action.
J. Biomol. Screen. 18(1) , 108-15, (2013) Organophosphates are a class of highly toxic chemicals that includes many pesticides and chemical weapons. Exposure to organophosphates, either through accidents or acts of terrorism, poses a significant risk to human health and safety. Existing antidotes, in... |
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Minimally invasive convection-enhanced delivery of biologics into dorsal root ganglia: validation in the pig model and prospective modeling in humans. Technical note.
J. Neurosurg. 121(4) , 851-8, (2014) Dorsal root ganglia (DRG) are critical anatomical structures involved in nociception. Intraganglionic (IG) drug delivery is therefore an important route of administration for novel analgesic therapies. Although IG injection in large animal models is highly de... |
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Isothermal microcalorimetry of pressurized systems II: effect of excipient and water ingress on formulation stability of amorphous glycopyrrolate.
Pharm. Res. 32(2) , 714-22, (2015) Use isothermal microcalorimetry to directly evaluate the effects of excipients and water content to produce a stable amorphous glycopyrrolate pressurized metered dose inhaler (pMDI) formulation.Amorphous glycopyrrolate particles with and without excipients (D... |