Thiabendazole
Thiabendazole structure
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Common Name | Thiabendazole | ||
|---|---|---|---|---|
| CAS Number | 148-79-8 | Molecular Weight | 201.248 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 446.0±37.0 °C at 760 mmHg | |
| Molecular Formula | C10H7N3S | Melting Point | 298-301ºC | |
| MSDS | Chinese USA | Flash Point | 226.2±16.9 °C | |
| Symbol |
GHS09 |
Signal Word | Warning | |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Chem. Res. Toxicol. 23 , 171-83, (2010) Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this st... |
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Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
J. Sci. Ind. Res. 65(10) , 808, (2006) Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be tra... |
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Pen-on-paper approach toward the design of universal surface enhanced Raman scattering substrates.
Small 10(15) , 3065-71, (2014) The translation of a technology from the laboratory into the real world should meet the demand of economic viability and operational simplicity. Inspired by recent advances in conductive ink pens for electronic devices on paper, we present a "pen-on-paper" ap... |
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Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
J. Med. Chem. 51 , 6740-51, (2008) The work provides a new model for the prediction of the MAO-A and -B inhibitor activity by the use of combined complex networks and QSAR methodologies. On the basis of the obtained model, we prepared and assayed 33 coumarin derivatives, and the theoretical pr... |
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Molecular characterization, fitness and mycotoxin production of benzimidazole-resistant isolates of Penicillium expansum.
Int. J. Food Microbiol. 162(3) , 237-44, (2013) Penicillium expansum field-strains resistant to benzimidazole fungicides were isolated in high frequency from decayed apple fruit collected from packinghouses and processing industries located in the region of Imathia, N. Greece. In vitro fungitoxicity tests ... |
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Spectrofluorometric and thermal gravimetric study on binding interaction of thiabendazole with hemoglobin on epoxy-functionalized magnetic nanoparticles.
Mater. Sci. Eng. C. Mater. Biol. Appl. 54 , 43-9, (2015) The interaction of thiabendazole (Tbz) with hemoglobin (Hb) on epoxy-functionalized iron oxide nanoparticles was presented in this study. The binding capacity of Tbz was determined by measuring at an excitation wavelength of 299 nm using fluorescence spectros... |
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Influence of pesticide use in fruit orchards during blooming on honeybee mortality in 4 experimental apiaries.
Sci. Total Environ. 541 , 33-41, (2015) Samples of dead honey bees (Apis mellifera L.) were collected periodically from 4 different locations during citrus and stone fruit trees blooming season to evaluate the potential impact of agrochemicals on honey bee death rate. For the determination of morta... |
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QSAR-based solubility model for drug-like compounds.
Bioorg. Med. Chem. 18 , 7078-84, (2010) Solubility plays a very important role in the selection of compounds for drug screening. In this context, a QSAR model was developed for predicting water solubility of drug-like compounds. First, a set of relevant parameters for establishing a drug-like chemi... |
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Multi-residue Determination of Polar Veterinary Drugs in Livestock and Fishery Products by Liquid Chromatography/Tandem Mass Spectrometry.
J. AOAC Int. 98(1) , 230-47, (2015) Residues of 37 polar veterinary drugs belonging to six families (quinolones, tetracyclines, macrolides, lincosamides, sulfonamides, and others) in livestock and fishery products were determined using a validated LC-MS/MS method. There were two key points in s... |
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Advanced electrolyte tuning and selectivity enhancement for highly sensitive analysis of cations by capillary ITP-ESI MS.
Electrophoresis 34(5) , 777-84, (2013) In this contribution we present an innovative way to easy, fast, and highly sensitive analyses by CE with ESI-MS detection. The new method is designed to be applied to ESI-compatible electrolytes (e.g. ammonium acetate) and offers advanced tuning of selectivi... |