Calmidazolium chloride
Calmidazolium chloride structure
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Common Name | Calmidazolium chloride | ||
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| CAS Number | 57265-65-3 | Molecular Weight | 687.698 | |
| Density | N/A | Boiling Point | 724.9ºC at 760mmHg | |
| Molecular Formula | C31H23Cl7N2O | Melting Point | 172-176ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nat. Chem. Biol. 5 , 765-71, (2009) Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened seven parasite lines for differences in responses to 1,279... |
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Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria.
Antimicrob. Agents Chemother. 53 , 5279-83, (2009) In this study, application of a dual absorbance/fluorescence assay to a chemical library screen identified several previously unknown inhibitors of mycobacteria. In addition, growth conditions had a significant effect on the activity profile of the library. S... |
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Evaluation of the calmodulin-SOX9 interaction by "magnetic fishing" coupled to mass spectrometry.
ChemBioChem. 15(16) , 2411-9, (2014) Disruption of calmodulin (CaM)-based protein interactions has been touted as a potential means for modulating several disease pathways. Among these is SOX9, which is a DNA binding protein that is involved in chrondrocyte differentiation and regulation of the ... |
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[Participation of proteinkinase CK2 in regulation of human erythrocytes plasma membrane redox system activity: relative contribution of ca(2+)-dependent and ca(2+)-independent mechanisms of its activation].
Ukr. Biokhim. Zh. 84(5) , 55-61, (2012) Involvement of protein kinase CK2 (2.7.11.1) in modulation of live cells trans-plasma membrane electron transport was first discovered. Using human erythrocytes a decrease of plasma membrane redox system (PMRS) activity is shown under the action of specific p... |
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Biochemical characterization of a recombinant Swainsona canescens calcium-dependent protein kinase (ScCPK1).
Plant Physiol. Biochem. 54 , 27-33, (2012) Calcium-dependent protein kinases (CPKs) constitute a unique family of kinases involved in many physiological responses in plants. Biochemical and kinetic properties of a recombinant Swainsona canescens calcium-dependent protein kinase (ScCPK1) were examined ... |
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Interactions of Bordetella pertussis adenylyl cyclase toxin CyaA with calmodulin mutants and calmodulin antagonists: comparison with membranous adenylyl cyclase I.
Biochem. Pharmacol. 83(7) , 839-48, (2012) The adenylyl cyclase (AC) toxin CyaA from Bordetella pertussis constitutes an important virulence factor for the pathogenesis of whooping cough. CyaA is activated by calmodulin (CaM) and compromises host defense by excessive cAMP production. Hence, pharmacolo... |
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LuxR-dependent quorum sensing: computer aided discovery of new inhibitors structurally unrelated to N-acylhomoserine lactones.
Bioorg. Med. Chem. Lett. 20 , 4355-8, (2010) A virtual screening, involving flexible docking sequences within the LuxR, TraR and LasR binding sites, was used as a structural binding sites similarity filter to specifically target conserved residues in the proteins of the LuxR family (namely Tyr62, Trp66,... |
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Regulation of store-operated Ca2+ entry in pulmonary artery smooth muscle cells.
Cell Calcium 46(2) , 99-106, (2009) Store-operated Ca2+ entry (SOCE) is an important mechanism for Ca2+ influx in smooth muscle cells; however the activation and regulation of this influx pathway are incompletely understood. In the present study we have examined the effect of several protein ki... |
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A role for calcium-calmodulin in regulating nitric oxide production during skeletal muscle satellite cell activation.
Am. J. Physiol. Cell Physiol. 296 , C922-9, (2009) When skeletal muscle is stretched or injured, myogenic satellite cells are activated to enter the cell cycle. This process depends on nitric oxide (NO) production by NO synthase (NOS), matrix metalloproteinase activation, release of hepatocyte growth factor (... |