(±)-Malic Acid
(±)-Malic Acid structure
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Common Name | (±)-Malic Acid | ||
|---|---|---|---|---|
| CAS Number | 6915-15-7 | Molecular Weight | 134.087 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 306.4±27.0 °C at 760 mmHg | |
| Molecular Formula | C4H6O5 | Melting Point | 131-133ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 153.4±20.2 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Urinary metabolic fingerprinting of mice with diet-induced metabolic derangements by parallel dual secondary column-dual detection two-dimensional comprehensive gas chromatography.
J. Chromatogr. A. 1361 , 265-76, (2014) This study investigates the potential of a parallel dual secondary column-dual detection two-dimensional comprehensive GC platform (GC×2GC-MS/FID) for metabolic profiling and fingerprinting of mouse urine. Samples were obtained from a murine model that mimics... |
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Ultrasonication as a potential tool to predict solute crystallization in freeze-concentrates.
Pharm. Res. 31(6) , 1512-24, (2014) We hypothesize that ultrasonication can accelerate solute crystallization in freeze-concentrates. Our objective is to demonstrate ultrasonication as a potential predictive tool for evaluating physical stability of excipients in frozen solutions.The crystalliz... |
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A metabolic-based approach to improve xylose utilization for fumaric acid production from acid pretreated wheat bran by Rhizopus oryzae.
Bioresour. Technol. 180 , 119-27, (2015) In this work, wheat bran (WB) was utilized as feedstock to synthesize fumaric acid by Rhizopus oryzae. Firstly, the pretreatment process of WB by dilute sulfuric acid hydrolysis undertaken at 100°C for 30min offered the best performance for fumaric acid produ... |
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Highly efficient extraction of anthocyanins from grape skin using deep eutectic solvents as green and tunable media.
Arch. Pharm. Res. 38 , 2143-52, (2015) Deep eutectic solvents (DESs) were investigated as tunable, environmentally benign, yet superior extraction media to enhance the extraction of anthocyanins from grape skin, which is usually discarded as waste. Ten DESs containing choline chloride as hydrogen ... |
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Structural characterization of a protective epitope spanning A(H1N1)pdm09 influenza virus neuraminidase monomers.
Nat. Commun. 6 , 6114, (2015) A(H1N1)pdm09 influenza A viruses predominated in the 2013-2014 USA influenza season, and although most of these viruses remain sensitive to Food and Drug Administration-approved neuraminidase (NA) inhibitors, alternative therapies are needed. Here we show tha... |
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Physiology and pathophysiology of organic acids in cerebrospinal fluid.
J. Inherit. Metab. Dis. 16(4) , 648-69, (1993) Concentrations of organic acids in cerebrospinal fluid (CSF) appear to be directly dependent upon their rate of production in the brain. There is evidence that the net release of short-chain monocarboxylic acids from the brain is a major route for removing th... |
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Antiviral effects of grape seed extract against feline calicivirus, murine norovirus, and hepatitis A virus in model food systems and under gastric conditions.
Food Microbiol. 52 , 1-10, (2015) Grape seed extract (GSE) has antiviral activities against hepatitis A virus (HAV) and human norovirus surrogates (feline calicivirus (FCV-F9) and murine norovirus (MNV-1)). The objectives of this study were to determine (1) time and dose-dependence of GSE aga... |
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C-phycocyanin prevents cisplatin-induced mitochondrial dysfunction and oxidative stress.
Mol. Cell Biochem. 406 , 183-97, (2015) The potential of C-phycocyanin (C-PC) to prevent cisplatin (CP)-induced kidney mitochondrial dysfunction was determined in CD-1 male mice. The CP-induced mitochondrial dysfunction was characterized by ultrastructural abnormalities and by decrease in the follo... |
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Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease.
J. Chromatogr. A. 562(1-2) , 125-38, (1991) Eighty-five clinical urine samples and nineteen urine samples previously found by other laboratories to suggest genetic metabolic defects were prepared for trimethylsilylation by treatment with urease, followed by azeotropic dehydration. The "Target Analyte S... |
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GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in db/db mice involved in diabetic nephropathy.
Am. J. Physiol. Renal Physiol. 304(11) , F1317-24, (2013) Early diagnosis of diabetic nephropathy (DN) is difficult although it is of crucial importance to prevent its development. To probe potential markers and the underlying mechanism of DN, an animal model of DN, the db/db mice, was used and serum and urine metab... |