(±)-Malic Acid

Modify Date: 2025-08-20 13:48:58

(±)-Malic Acid structure	Common Name	(±)-Malic Acid
	CAS Number	6915-15-7	Molecular Weight	134.087
	Density	1.6±0.1 g/cm3	Boiling Point	306.4±27.0 °C at 760 mmHg
	Molecular Formula	C₄H₆O₅	Melting Point	131-133ºC(lit.)
	MSDS	Chinese USA	Flash Point	153.4±20.2 °C
	Symbol	GHS07	Signal Word	Warning

Use of (±)-Malic Acid

Malic acid is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods.

Name	malic acid
Synonym	More Synonyms

Description	Malic acid is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods.
Related Catalog	Research Areas >> Others
Target	Human Endogenous Metabolite
References	[1]. Dai Z, et al. Current advance in biological production of malic acid using wild type and metabolic engineered strains. Bioresour Technol. 2018 Jun;258:345-353.

Density	1.6±0.1 g/cm3
Boiling Point	306.4±27.0 °C at 760 mmHg
Melting Point	131-133ºC(lit.)
Molecular Formula	C₄H₆O₅
Molecular Weight	134.087
Flash Point	153.4±20.2 °C
Exact Mass	134.021530
PSA	94.83000
LogP	-1.26
Vapour density	4.6 (vs air)
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.529
Storage condition	2-8°C
Water Solubility	methanol: 0.1 g/mL, clear, colorless \| 558 g/L (20 ºC)

(±)-Malic Acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ON7175000

CHEMICAL NAME :: Malic acid

CAS REGISTRY NUMBER :: 6915-15-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C4-H6-O5

MOLECULAR WEIGHT :: 134.10

WISWESSER LINE NOTATION :: QVYQ1VQ -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,657,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,657,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4937,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: #82-0458

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4937,1982 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1766 No. of Facilities: 1278 (estimated) No. of Industries: 11 No. of Occupations: 21 No. of Employees: 8629 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1766 No. of Facilities: 3524 (estimated) No. of Industries: 44 No. of Occupations: 46 No. of Employees: 80674 (estimated) No. of Female Employees: 51609 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P280-P305 + P351 + P338-P337 + P313
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	ON7175000
HS Code	2918990090

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Urinary metabolic fingerprinting of mice with diet-induced metabolic derangements by parallel dual secondary column-dual detection two-dimensional comprehensive gas chromatography.

J. Chromatogr. A. 1361 , 265-76, (2014)

This study investigates the potential of a parallel dual secondary column-dual detection two-dimensional comprehensive GC platform (GC×2GC-MS/FID) for metabolic profiling and fingerprinting of mouse u...

Ultrasonication as a potential tool to predict solute crystallization in freeze-concentrates.

Pharm. Res. 31(6) , 1512-24, (2014)

We hypothesize that ultrasonication can accelerate solute crystallization in freeze-concentrates. Our objective is to demonstrate ultrasonication as a potential predictive tool for evaluating physical...

A metabolic-based approach to improve xylose utilization for fumaric acid production from acid pretreated wheat bran by Rhizopus oryzae.

Bioresour. Technol. 180 , 119-27, (2015)

In this work, wheat bran (WB) was utilized as feedstock to synthesize fumaric acid by Rhizopus oryzae. Firstly, the pretreatment process of WB by dilute sulfuric acid hydrolysis undertaken at 100°C fo...

hydroxy-butanedioic acid

MFCD00064212

R,S(±)-Malic acid

Butanedioic acid, hydroxy-

alpha-Hydroxysuccinic acid

(±)-1-Hydroxy-1,2-ethanedicarboxylic Acid

UNII:817L1N4CKP

Butanedioic acid, 2-hydroxy-

Hydroxybutandisaeure

alpha-hydroxysuccinicacid

MALIC ACID, (DL)

hydroxysuccinic acid

DL(+/-)-MALIC ACID

R,S-Malic acid

2-hydroxybutane-1,4-dioic acid

EINECS 210-514-9

2-hydroxybutanedioic acid

2-Hydroxysuccinic Acid

a-Hydroxysuccinic Acid

Malic acid

Malic acid, dl-

DL-MALIC ACID

2-Hydroxy-succinic acid

DL-Hydroxybutanedioic acid

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (±)-Malic Acid
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China
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DC Chemicals Limited
China
Product Name: Malic acid
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China
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Delivery: Inquiry
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: malic acid
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
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Delivery: Inquiry
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(±)-Malic Acid

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