(±)-Malic Acid
Names
[ CAS No. ]:
6915-15-7
[ Name ]:
(±)-Malic Acid
[Synonym ]:
hydroxy-butanedioic acid
MFCD00064212
R,S(±)-Malic acid
Butanedioic acid, hydroxy-
alpha-Hydroxysuccinic acid
(±)-1-Hydroxy-1,2-ethanedicarboxylic Acid
UNII:817L1N4CKP
Butanedioic acid, 2-hydroxy-
Hydroxybutandisaeure
alpha-hydroxysuccinicacid
MALIC ACID, (DL)
hydroxysuccinic acid
DL(+/-)-MALIC ACID
R,S-Malic acid
2-hydroxybutane-1,4-dioic acid
EINECS 210-514-9
2-hydroxybutanedioic acid
2-Hydroxysuccinic Acid
a-Hydroxysuccinic Acid
Malic acid
Malic acid, dl-
DL-MALIC ACID
2-Hydroxy-succinic acid
DL-Hydroxybutanedioic acid
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Human Endogenous Metabolite
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
306.4±27.0 °C at 760 mmHg
[ Melting Point ]:
131-133ºC(lit.)
[ Molecular Formula ]:
C4H6O5
[ Molecular Weight ]:
134.087
[ Flash Point ]:
153.4±20.2 °C
[ Exact Mass ]:
134.021530
[ PSA ]:
94.83000
[ LogP ]:
-1.26
[ Vapour density ]:
4.6 (vs air)
[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C
[ Index of Refraction ]:
1.529
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
methanol: 0.1 g/mL, clear, colorless | 558 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ON7175000
- CHEMICAL NAME :
- Malic acid
- CAS REGISTRY NUMBER :
- 6915-15-7
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C4-H6-O5
- MOLECULAR WEIGHT :
- 134.10
- WISWESSER LINE NOTATION :
- QVYQ1VQ -L
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,657,1986
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,657,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4937,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: #82-0458
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4937,1982 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1766 No. of Facilities: 1278 (estimated) No. of Industries: 11 No. of Occupations: 21 No. of Employees: 8629 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1766 No. of Facilities: 3524 (estimated) No. of Industries: 44 No. of Occupations: 46 No. of Employees: 80674 (estimated) No. of Female Employees: 51609 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H319
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P337 + P313
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
ON7175000
[ HS Code ]:
2918990090
Customs
[ HS Code ]: 2918990090
[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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