2-Methylthiirane

2-Methylthiirane Structure
2-Methylthiirane structure
Common Name 2-Methylthiirane
CAS Number 1072-43-1 Molecular Weight 74.145
Density 1.0±0.1 g/cm3 Boiling Point 75.9±8.0 °C at 760 mmHg
Molecular Formula C3H6S Melting Point N/A
MSDS Chinese USA Flash Point 10.0±0.0 °C
Symbol GHS02 GHS06
GHS02, GHS06
Signal Word Danger

Enhanced tumor-targeted gene delivery by bioreducible polyethylenimine tethering EGFR divalent ligands.

Biomater. Sci. 3 , 1096-104, (2015)

This work demonstrates successful delivery of a gene to EGFR-overexpressed cancer cells by using a rationally designed branched GE11 peptide as a targeting ligand. In addition, we exploited the effect of the divalent structure of the branched GE11 peptide on ...

S-Nitrosated Polypropylene Sulfide Nanoparticles for Thiol-Dependent Transnitrosation and Toxicity Against Adult Female Filarial Worms.

Adv. Healthc. Mater. 4(10) , 1484-90, 1423, (2015)

A synthetic polymer nanoparticle formulation utilizing the physiological nitrosothiol chemistry for nitric oxide delivery is shown. Toxicity of S-nitroso nanoparticles against adult female Brugia malayi worms, which are responsible for lymphatic filariasis, i...

Preparing a pseudo-solid by the reinforcement of a polydentate thioether using silver nanoparticles.

Nanoscale 7(5) , 1977-83, (2015)

The design of networks from polymers and noble metal nanoparticles requires thorough control over topological polymer-particle arrangements. This study explores the interaction between a linear polydentate poly(propylene sulfide) (PPrS) ligand and silver nano...

Bioreducible guanidinylated polyethylenimine for efficient gene delivery.

ChemMedChem 9(12) , 2718-24, (2014)

Cationic polymers are known to afford efficient gene transfection. However, cytotoxicity remains a problem at the molecular weight for optimal DNA delivery. As such, optimized polymeric gene delivery systems are still a sought-after research goal. A guanidiny...

Chemisorbed poly(propylene sulphide)-based copolymers resist biomolecular interactions.

Nat. Mater. 2(4) , 259-64, (2003)

Alkanethiolates have been widely used as chemisorbates to modify gold surfaces, in spite of their relatively poor oxidative stability. We introduce gold-chemisorbing block copolymers bearing an anchoring block of poly(propylene sulphide) (PPS), selected in th...

Reduction-sensitive tioguanine prodrug micelles.

Mol. Pharm. 9(10) , 2812-8, (2012)

Colloidal drug and prodrug conjugates have unique targeting characteristics for tumor vasculature from the blood and for the lymphatics draining a tissue injection site. Tioguanine and tioguanine-generating prodrugs have been investigated as anticancer and im...

Diffusion NMR spectroscopy for the characterization of the size and interactions of colloidal matter: the case of vesicles and nanoparticles.

J. Am. Chem. Soc. 126(7) , 2142-7, (2004)

We report the application of the pulse gradient spin-echo (PGSE) NMR technique (PGSE NMR) to the analysis of large colloidal materials, specifically vesicles formed from macromolecular amphiphiles and nanoparticles. Measurements of size and size distribution ...

The chiroptical signature of achiral metal clusters induced by dissymmetric adsorbates.

Phys. Chem. Chem. Phys. 8(1) , 63-7, (2006)

Using a dissymmetrically-perturbed particle-in-a-box model, we demonstrate that the induced optical activity of chiral monolayer protected clusters, such as Whetten's Au28(SG)16 glutathione-passivated gold nanoclusters (J. Phys. Chem. B, 2000, 104, 2630-2641)...

Combination of episulfide ring-opening polymerization with ATRP for the preparation of amphiphilic block copolymers.

Macromol. Rapid Commun. 34(2) , 156-62, (2013)

We report for the first time the combination of ATRP and ring-opening episulfide polymerization as a means to synthesize polysulfide-based low-dispersity amphiphilic block copolymers. The most significant finding is the possibility to perform ATRP under mild ...

Constellational diastereomers in encapsulation complexes.

Chem. Commun. (Camb.) (15) , 1690-1, (2004)

Three chiral guests in a cylindrical capsule led to six diastereomeric complexes.