9-Aminoacridine

9-Aminoacridine Structure
9-Aminoacridine structure
Common Name 9-Aminoacridine
CAS Number 90-45-9 Molecular Weight 194.23200
Density 1.268g/cm3 Boiling Point 413.5ºC at 760 mmHg
Molecular Formula C13H10N2 Melting Point 241ºC
MSDS Chinese USA Flash Point 233.2ºC
Symbol GHS07
GHS07
Signal Word Warning

Genotoxicity testing of esterified propoxylated glycerol (EPG).

Regul Toxicol Pharmacol 70 Suppl 2 , S131-42, (2014)

Four versions of esterified propoxylated glycerols (EPGs) were evaluated for potential genotoxicity using a range of in vitro and in vivo assays. H-EPG-05 HR/SO 9:1, H-EPG-05 soyate, and H-EPG-14 soyate were non-mutagenic in reverse mutation assays (maximum c...

Mutagenicity and DNA-damaging potential of clenbuterol and its metabolite 4-amino-3,5-dichlorobenzoic acid in vitro.

Food Chem. Toxicol. 77 , 82-92, (2015)

The aim of this study was to evaluate in vitro toxicity of clenbuterol and its metabolite 4-amino-3,5-dichlorobenzoic acid. Cytotoxicity and pro-oxidative effect of both compounds were studied on human colon adenocarcinoma cell line SW 480. No significant cyt...

Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.

J. Lipid Res. 55(11) , 2354-69, (2014)

Mammalian kidneys are rich in sulfatides. Papillary sulfatides, especially, contribute to renal adaptation to chronic metabolic acidosis. Due to differences in their cer-amide (Cer) anchors, the structural diversity of renal sulfatides is large. However, the ...

Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2009-2010.

Mass Spectrom. Rev. 34(3) , 268-422, (2015)

This review is the sixth update of the original article published in 1999 on the application of MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings coverage of the literature to the end of 2010. General aspects such as theo...

Optimization of matrix assisted desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) for the characterization of Bacillus and Brevibacillus species.

Anal. Chim. Acta 840 , 49-57, (2014)

Over the past few decades there has been an increased interest in using various analytical techniques for detecting and identifying microorganisms. More recently there has been an explosion in the application of matrix assisted laser desorption ionization tim...

Distribution study of atorvastatin and its metabolites in rat tissues using combined information from UHPLC/MS and MALDI-Orbitrap-MS imaging.

Anal. Bioanal. Chem 406(19) , 4601-10, (2014)

The combination of ultrahigh-resolution mass spectrometry imaging (UHRMSI) and ultrahigh-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC/MS/MS) was used for the identification and the spatial localization of atorvastatin (AT) an...

Two antigenotoxic chalcone glycosides from Mentha longifolia subsp. longifolia.

Pharm. Biol. 53(6) , 888-96, (2015)

Mentha L. (Labiatae) species (mint) with their flavoring properties have been used in food industries for centuries. Besides they have a great importance in drug development and medicinal applications due to various bioactive compounds of several members of t...

Safety evaluation of the human-identical milk monosaccharide sialic acid (N-acetyl-d-neuraminic acid) in Sprague-Dawley rats.

Regul Toxicol Pharmacol 70(2) , 482-91, (2014)

N-Acetyl-d-neuraminic acid (Neu5Ac) is the predominant form of sialic acid (Sia) in humans, while other mammals express Sia as a mixture with N-glycolyl-d-neuraminic acid (Neu5Gc). Neu5Ac occurs in highest levels in the brain and in breast milk, and is theref...

Mutagenicity and tumor-promoting effects of Tiglium seed extract via PKC and MAPK signaling pathways.

Biosci. Biotechnol. Biochem. 79(3) , 374-83, (2015)

Tiglium seed is a seed of mature Croton Tiglium Linne containing croton oils, which have been traditionally used as laxative or purgative. As it contains phorbol derivatives, we investigated the mutagenicity and tumor-promoting activity of Tiglium seed. Tigli...

Mutagenicity and genotoxicity studies of arruva, an R,R-monatin salt isomer

Food Chem. Toxicol. 68 , 30-7, (2014)

• Arruva; i.e., the R,R-isomer of monatin, did not cause bacterial reverse mutations in an Ames assay. • Arruva did not induce mutations in a mouse lymphoma assay. • Arruva did not increase the incidence of micronucleated polychromatic erythrocytes in an in v...