9-Aminoacridine

Modify Date: 2024-01-09 18:47:56

9-Aminoacridine Structure
9-Aminoacridine structure
Common Name 9-Aminoacridine
CAS Number 90-45-9 Molecular Weight 194.23200
Density 1.268g/cm3 Boiling Point 413.5ºC at 760 mmHg
Molecular Formula C13H10N2 Melting Point 241ºC
MSDS Chinese USA Flash Point 233.2ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of 9-Aminoacridine


9-Aminoacridine is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator.

 Names

Name 9-aminoacridine
Synonym More Synonyms

 9-Aminoacridine Biological Activity

Description 9-Aminoacridine is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator.
Related Catalog

 Chemical & Physical Properties

Density 1.268g/cm3
Boiling Point 413.5ºC at 760 mmHg
Melting Point 241ºC
Molecular Formula C13H10N2
Molecular Weight 194.23200
Flash Point 233.2ºC
Exact Mass 194.08400
PSA 38.91000
LogP 3.55140
Index of Refraction 1.78
Stability Stable. Incompatible with strong oxidizing agents.
Water Solubility ethanol: hazy

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AR7300000
CHEMICAL NAME :
Acridine, 9-amino-
CAS REGISTRY NUMBER :
90-45-9
BEILSTEIN REFERENCE NO. :
0141171
LAST UPDATED :
199710
DATA ITEMS CITED :
32
MOLECULAR FORMULA :
C13-H10-N2
MOLECULAR WEIGHT :
194.25
WISWESSER LINE NOTATION :
T C666 BNJ IZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
68 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory stimulation
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
Specific locus test
TYPE OF TEST :
Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
10 mmol/L
REFERENCE :
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 44,53,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - B0081 No. of Facilities: 75 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 299 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR 2811
WGK Germany 3
RTECS AR7300000
Packaging Group III
Hazard Class 6.1(b)

 Articles55

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Mutagenicity and DNA-damaging potential of clenbuterol and its metabolite 4-amino-3,5-dichlorobenzoic acid in vitro.

Food Chem. Toxicol. 77 , 82-92, (2015)

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Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.

J. Lipid Res. 55(11) , 2354-69, (2014)

Mammalian kidneys are rich in sulfatides. Papillary sulfatides, especially, contribute to renal adaptation to chronic metabolic acidosis. Due to differences in their cer-amide (Cer) anchors, the struc...

 Synonyms

MFCD00037839
EINECS 201-995-6
9-Aminoacridine
9-aminoacridiniun
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