spiraeoside
spiraeoside structure
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Common Name | spiraeoside | ||
|---|---|---|---|---|
| CAS Number | 20229-56-5 | Molecular Weight | 464.37600 | |
| Density | 1.809g/cm3 | Boiling Point | 835.6ºC at 760mmHg | |
| Molecular Formula | C21H20O12 | Melting Point | 209-211ºC | |
| MSDS | Chinese USA | Flash Point | 294.6ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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The crystal structure of human cytosolic beta-glucosidase unravels the substrate aglycone specificity of a family 1 glycoside hydrolase.
J. Mol. Biol. 370(5) , 964-75, (2007) Human cytosolic beta-glucosidase (hCBG) is a xenobiotic-metabolizing enzyme that hydrolyses certain flavonoid glucosides, with specificity depending on the aglycone moiety, the type of sugar and the linkage between them. In this study, the substrate preferenc... |
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Flavonoid glycosides inhibit oral cancer cell proliferation--role of cellular uptake and hydrolysis to the aglycones.
J. Pharm. Pharmacol. 57(8) , 1037-42, (2005) Epidemiologic evidence supports the view that dietary flavonoids exert protective effects in oral diseases, including cancer. However, the dietary forms of flavonoids, the flavonoid glycosides, are thought to be inactive, thus they must first be hydrolysed to... |
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Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity.
FEBS Lett. 436(1) , 71-5, (1998) Flavonoid and isoflavonoid glycosides are common dietary phenolics which may be absorbed from the small intestine of humans. The ability of cell-free extracts from human small intestine and liver to deglycosylate various (iso)flavonoid glycosides was investig... |
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Quercetin glucosides inhibit glucose uptake into brush-border-membrane vesicles of porcine jejunum.
Br. J. Nutr. 91(6) , 849-55, (2004) Recent experimental data point to an interaction of dietary flavonol monoglucosides with the intestinal Na-dependent glucose transporter 1 (SGLT1). To investigate this interaction in more detail, we performed experiments with SGLT1-containing brush-border-mem... |
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Disposition and metabolism of [2-14C]quercetin-4'-glucoside in rats.
Drug Metab. Dispos. 33(7) , 1036-43, (2005) Quercetin-4'-glucoside is a major flavonol in onions, and this study investigated the absorption and fate of radiolabeled quercetin-4'-glucoside in rats. Rats ingested [2-(14)C]quercetin-4'-glucoside and the distribution of radioactivity throughout the body w... |
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Pharmacokinetics and bioavailability of quercetin glycosides in humans.
J. Clin. Pharmacol. 41(5) , 492-9, (2001) Due to its potentially beneficial impact on human health, the polyphenol quercetin has come into the focus of medicinal interest. However, data on the bioavailability of quercetin after oral intake are scarce and contradictory. Previous investigations indicat... |
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Quercetin-4'-glucoside is more potent than quercetin-3-glucoside in protection of rat intestinal mucosa homogenates against iron ion-induced lipid peroxidation.
J. Agric. Food Chem. 52(7) , 1907-12, (2004) Quercetin is a typical antioxidative flavonoid found in vegetables, which is more commonly present as its glucosides, quercetin-3-glucoside (Q3G) and quercetin-4'-glucoside (Q4'G). The main aim of this study was to estimate the antioxidant activity of Q3G and... |
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Interaction of quercetin glucosides with the intestinal sodium/glucose co-transporter (SGLT-1).
Cancer Lett. 162(2) , 175-80, (2001) Recently it has been postulated that flavonoid glucosides may be absorbed by the small intestine via the SGLT-1. Therefore, we applied an in vitro mucosal uptake method to investigate mucosal uptake of the non-metabolisable glucose analogue methyl-alpha-D-glu... |
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Efficiency of absorption and metabolic conversion of quercetin and its glucosides in human intestinal cell line Caco-2.
Arch. Biochem. Biophys. 384(2) , 391-7, (2000) The efficiency of intestinal absorption and metabolic conversion of quercetin aglycone and its glucosides, quercetin-4'-O-beta-D-glucoside (Q4'G), quercetin-3-O-beta-D-glucoside (Q3G), and quercetin-3,4'-di-O-beta-D-glucoside (Q3,4'G), was estimated by using ... |
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In vitro digestion and lactase treatment influence uptake of quercetin and quercetin glucoside by the Caco-2 cell monolayer.
Nutr. J. 4 , 1, (2005) Quercetin and quercetin glycosides are widely consumed flavonoids found in many fruits and vegetables. These compounds have a wide range of potential health benefits, and understanding the bioavailability of flavonoids from foods is becoming increasingly impo... |