spiraeoside
Modify Date: 2024-01-02 09:09:38
spiraeoside structure
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Common Name | spiraeoside | ||
|---|---|---|---|---|
| CAS Number | 20229-56-5 | Molecular Weight | 464.37600 | |
| Density | 1.809g/cm3 | Boiling Point | 835.6ºC at 760mmHg | |
| Molecular Formula | C21H20O12 | Melting Point | 209-211ºC | |
| MSDS | Chinese USA | Flash Point | 294.6ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of spiraeosideSpiraeoside, an orally active natural compound, exerts antioxidant activity, inhibits reactive oxygen species (ROS) and malondialdehyde production. Spiraeoside possesses antiallergic, anti-inflammatory and antitumor activities[1]. |
| Name | quercetin 4ʼ-O-β-D-glucopyranoside |
|---|---|
| Synonym | More Synonyms |
| Description | Spiraeoside, an orally active natural compound, exerts antioxidant activity, inhibits reactive oxygen species (ROS) and malondialdehyde production. Spiraeoside possesses antiallergic, anti-inflammatory and antitumor activities[1]. |
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| Related Catalog | |
| In Vitro | Spiraeoside elevates HG stimulation-caused the decrease in the expression levels of p-Akt, nuclear Nrf2, and HO-1 in AC16 cells (the effects of Spiraeoside are reversedby LY294002)[1]. Spiraeoside protects AC16 cells against HG-induced oxidative stress, cell injury, and apoptosis[1]. Spiraeoside activates the PI3K/Akt/Nrf2 pathway in AC16 cells on exposure to HG[1]. Spiraeoside protects AC16 cells against HG-induced apoptosis through the PI3K/Akt/Nrf2 pathway[1]. Cell Viability Assay[1] Cell Line: AC16 cells. Concentration: 1, 5, 10, or 20 μM. Incubation Time: 0, 24, or 48 hours. Result: Inhibited AC16 cells viability (20 μM). |
| In Vivo | Spiraeoside (50 mg/kg, p.o.) shows ulcer preventive ability[2]. Animal Model: Male Wistar rats (6-8 weeks old)[2]. Dosage: 50 mg/kg. Administration: Oral gavage an hour before inducing the lesions. Result: Decreased severity of the formed lesions. |
| References |
| Density | 1.809g/cm3 |
|---|---|
| Boiling Point | 835.6ºC at 760mmHg |
| Melting Point | 209-211ºC |
| Molecular Formula | C21H20O12 |
| Molecular Weight | 464.37600 |
| Flash Point | 294.6ºC |
| Exact Mass | 464.09500 |
| PSA | 210.51000 |
| Vapour Pressure | 1.28E-29mmHg at 25°C |
| Index of Refraction | 1.774 |
| Storage condition | ?20°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
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CAS#:1313191-85-3
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The crystal structure of human cytosolic beta-glucosidase unravels the substrate aglycone specificity of a family 1 glycoside hydrolase.
J. Mol. Biol. 370(5) , 964-75, (2007) Human cytosolic beta-glucosidase (hCBG) is a xenobiotic-metabolizing enzyme that hydrolyses certain flavonoid glucosides, with specificity depending on the aglycone moiety, the type of sugar and the l... |
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Flavonoid glycosides inhibit oral cancer cell proliferation--role of cellular uptake and hydrolysis to the aglycones.
J. Pharm. Pharmacol. 57(8) , 1037-42, (2005) Epidemiologic evidence supports the view that dietary flavonoids exert protective effects in oral diseases, including cancer. However, the dietary forms of flavonoids, the flavonoid glycosides, are th... |
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Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity.
FEBS Lett. 436(1) , 71-5, (1998) Flavonoid and isoflavonoid glycosides are common dietary phenolics which may be absorbed from the small intestine of humans. The ability of cell-free extracts from human small intestine and liver to d... |
| Spiraeosid |
| Quercetin 4'-b-D-glucopyranoside |
| Quercetin 4'-O-glucoside |
| Quercetin-4'-glucoside |
| EINECS 243-614-6 |
| Spiraein |
| 3,5,7-trihydroxy-2-[3-hydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one |
| quercetin 4'-O-beta-D-glucopyranoside |
| Spiraeoside |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: spiraeoside
- Price: ￥2678.0/10mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Spiraeoside
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: SPIRAEOSIDE
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
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Price: ￥10920/50mg
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