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苯并呋喃

一般危化品
苯并呋喃结构式
苯并呋喃结构式
常用名 苯并呋喃 英文名 Coumarone
CAS号 271-89-6 分子量 118.133
密度 1.1±0.1 g/cm3 沸点 174.0±0.0 °C at 760 mmHg
分子式 C8H6O 熔点 -18ºC
MSDS 中文版 美版 闪点 56.1±0.0 °C
符号 GHS02 GHS08
GHS02, GHS08
信号词 Warning

Rational design of novel CYP2A6 inhibitors.

Bioorg. Med. Chem. 22(23) , 6655-64, (2015)

Inhibition of CYP2A6-mediated nicotine metabolism can reduce cigarette smoking. We sought potent and selective CYP2A6 inhibitors to be used as leads for drugs useful in smoking reduction therapy, by evaluating CYP2A6 inhibitory effect of novel formyl, alkyl a...

Cyclooxygenase 2 inhibitor celecoxib inhibits glutamate release by attenuating the PGE2/EP2 pathway in rat cerebral cortex endings.

J. Pharmacol. Exp. Ther. 351(1) , 134-45, (2014)

The excitotoxicity caused by excessive glutamate is a critical element in the neuropathology of acute and chronic brain disorders. Therefore, inhibition of glutamate release is a potentially valuable therapeutic strategy for treating these diseases. In this s...

Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.

Biochim. Biophys. Acta 1838(10) , 2484-91, (2014)

CLC-K chloride channels play a crucial role in kidney physiology and genetic mutations, affecting their function are responsible for severe renal salt loss in humans. Thus, compounds that selectively bind to CLC-Ka and/or CLC-Kb channels and modulate their ac...