Coumarone
Coumarone structure
|
Common Name | Coumarone | ||
|---|---|---|---|---|
| CAS Number | 271-89-6 | Molecular Weight | 118.133 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 174.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C8H6O | Melting Point | -18ºC | |
| MSDS | Chinese USA | Flash Point | 56.1±0.0 °C | |
| Symbol |
GHS02, GHS08 |
Signal Word | Warning | |
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Rational design of novel CYP2A6 inhibitors.
Bioorg. Med. Chem. 22(23) , 6655-64, (2015) Inhibition of CYP2A6-mediated nicotine metabolism can reduce cigarette smoking. We sought potent and selective CYP2A6 inhibitors to be used as leads for drugs useful in smoking reduction therapy, by evaluating CYP2A6 inhibitory effect of novel formyl, alkyl a... |
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Cyclooxygenase 2 inhibitor celecoxib inhibits glutamate release by attenuating the PGE2/EP2 pathway in rat cerebral cortex endings.
J. Pharmacol. Exp. Ther. 351(1) , 134-45, (2014) The excitotoxicity caused by excessive glutamate is a critical element in the neuropathology of acute and chronic brain disorders. Therefore, inhibition of glutamate release is a potentially valuable therapeutic strategy for treating these diseases. In this s... |
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Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.
Biochim. Biophys. Acta 1838(10) , 2484-91, (2014) CLC-K chloride channels play a crucial role in kidney physiology and genetic mutations, affecting their function are responsible for severe renal salt loss in humans. Thus, compounds that selectively bind to CLC-Ka and/or CLC-Kb channels and modulate their ac... |