1,2-环己二酮
1,2-环己二酮结构式
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常用名 | 1,2-环己二酮 | 英文名 | 1,2-Cyclohexanedione |
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| CAS号 | 765-87-7 | 分子量 | 112.127 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 194.0±9.0 °C at 760 mmHg | |
| 分子式 | C6H8O2 | 熔点 | 35 °C | |
| MSDS | 中文版 美版 | 闪点 | 66.9±4.4 °C |
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Chemical modification of cationic groups in the polypeptide cardiac stimulant anthopleurin-A.
Toxicon 33(2) , 187-99, (1995) Chemical modification studies have been carried out on the sea anemone polypeptide anthopleurin-A in order to clarify the role of Arg-14 in its cardiac stimulatory activity. Reaction with 1,2-cyclohexanedione at 37 degrees C produced a range of protein produc... |
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Modification of arginine-198 in sarcoplasmic reticulum Ca2+-ATPase by 1,2-cyclohexanedione causes inhibition of formation of the phosphoenzyme intermediate from inorganic phosphate.
J. Biol. Chem. 272(34) , 21142-50, (1997) Sarcoplasmic reticulum vesicles were modified with 1,2-cyclohexanedione (CHD), a specific arginine-modifying reagent, in sodium borate (pH 8.0 or 8.8). Phosphoenzyme formation from Pi in the Ca2+-ATPase (reversal of hydrolysis of the phosphoenzyme intermediat... |
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Evidence for an essential arginine in the flavoprotein nitroalkane oxidase.
J. Enzym. Inhib. 16(2) , 157-63, (2001) The flavoprotein nitroalkane oxidase from the fungus Fusarium oxysporum catalyzes the oxidative denitrification of primary or secondary nitroalkanes to yield the respective aldehydes or ketones, hydrogen peroxide and nitrite. The enzyme is inactivated in a ti... |
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Modification of arginine residues in ovine prolactin by 1,2-cyclohexanedione. Effect on binding capacity to lactogenic receptors.
Int. J. Pept. Protein Res. 44(1) , 31-5, (1994) The reactivity of arginine residues in ovine prolactin was studied by reaction with 1,2-cyclohexanedione. Kinetic analysis of the data showed a good fit with two simultaneous pseudo-first-order equations with apparent velocity constants of 0.28 and 1.2 x 10(-... |
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Identification of arginyl residues located at the ATP binding site of sarcoplasmic reticulum Ca2+-ATPase. Modification with 1,2-cyclohexanedione.
J. Biol. Chem. 271(46) , 28933-41, (1996) Sarcoplasmic reticulum vesicles were treated with 1, 2-cyclohexanedione (CHD) in sodium borate (pH 8.0). The Ca2+-ATPase activity was completely inhibited. Inhibition of Mg.ATP and Mg.ADP binding to the high affinity ATP binding site as well as inhibition of ... |
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Albumin reduces basement membrane hydraulic conductance in part due to arginyl side groups.
Am. J. Physiol. 269(5 Pt 2) , H1514-21, (1995) Albumin reduces capillary hydraulic conductance (Lp) even at low concentrations. To determine if part of this barrier protective effect might be extracellular, we studied the effects of bovine serum albumin (BSA) on Lp of self-assembled basement membrane (Mat... |
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Synthesis of new dihydropyrazines with DNA strand-breakage activity.
Chem. Pharm. Bull. 53(10) , 1359-61, (2005) Treatment of 1,2-cyclohexanedione with 1,2-diamines, e.g. ethylenediamine and cis-(and trans-)1,2-diaminocyclohexane, caused [4+2] cyclocondensation to give the corresponding dihydropyrazine derivatives (compounds 1-6). They exhibited stronger DNA strand-brea... |
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Differences in the active site environment of Aspergillus ficuum phytases.
Biochem. Biophys. Res. Commun. 243(2) , 458-62, (1998) While Aspergillus ficuum phytaseA (phyA) was rapidly inactivated by 1,2-cyclohexanedione and phenylglyoxal, both specific modifiers of arginine, phytaseB (phyB) showed a markedly different behavior. First, phyB was totally insensitive to 1,2-cyclohexanedione ... |
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Identification of arg-30 as the essential residue for the enzymatic activity of Taiwan cobra phospholipase A2.
J. Biochem. 124(4) , 764-8, (1998) Taiwan cobra (Naja naja atra) phospholipase A2 (PLA2) was inactivated by arginine-specific reagents, phenylglyoxal and 1, 2-cyclohexanedione. Kinetic analyses of the modification reaction revealed that the inactivation of PLA2 followed pseudo-first-order kine... |
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Chemical modification of the arginyl residue in silk fibroin: 2. Reaction of 1,2-cyclohexanedione in aqueous alkaline medium.
Int. J. Biol. Macromol. 19(1) , 41-4, (1996) The arginyl residue of solubilized silk fibroin was chemically modified with 1,2-cyclohexanedione in aqueous alkaline medium to form a stable imidazolidinone ring, and its positive charge was masked. CD spectra of the modified silk fibroin in aqueous solution... |