(±)-DOI 盐酸盐
(±)-DOI 盐酸盐结构式
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常用名 | (±)-DOI 盐酸盐 | 英文名 | UNII:Q2E57V2WS3 |
|---|---|---|---|---|
| CAS号 | 42203-78-1 | 分子量 | 357.616 | |
| 密度 | N/A | 沸点 | 361.5ºC at 760 mmHg | |
| 分子式 | C11H17ClINO2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 172.5ºC | |
| 符号 |
GHS02, GHS06, GHS08 |
信号词 | Danger |
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LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex.
J. Pharmacol. Exp. Ther. 278 , 1373-1382, (1996) Correlations between 5-hydroxytryptamine (5-HT) receptor binding affinities and human hallucinogenic potency have suggested that 5-HT2 receptors mediate the hallucinogenic effects of lysergic acid diethylamide (LSD) and phenethylamine hallucinogens. Electroph... |
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Effect of the selective 5-HT receptor agonists 8-OHDPAT and DOI on behavior and brain biogenic amines of rats.
Gen. Pharmacol. 28 , 583-587, (1997) 1. The behavioral responses, as well as the biogenic amines and metabolite contents in discrete brain areas were determined in male rats subcutaneously treated with a 5-HT1A (8-OHDPAT) or 5-HT2A (DOI) agonist at doses (0.5-2 mg/kg) sufficient to produce the t... |
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DOI, a 5-HT2A/2C receptor agonist, potentiates amphetamine-induced dopamine release in rat striatum.
Brain Res. 698 , 204-208, (1995) The effects of (+-)-DOI (1-(2,5-dimethoxy-4-iodophenyl)-aminopropane) hydrochloride, a mixed 5-HT2A/2C receptor agonist, on the release of dopamine (DA) following D-amphetamine sulfate (AMP) or a DA D2 autoreceptor selective dose of (-)-apomorphine hydrochlor... |