UNII:Q2E57V2WS3

UNII:Q2E57V2WS3 Structure
UNII:Q2E57V2WS3 structure
Common Name UNII:Q2E57V2WS3
CAS Number 42203-78-1 Molecular Weight 357.616
Density N/A Boiling Point 361.5ºC at 760 mmHg
Molecular Formula C11H17ClINO2 Melting Point N/A
MSDS Chinese USA Flash Point 172.5ºC
Symbol GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
Signal Word Danger

LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex.

J. Pharmacol. Exp. Ther. 278 , 1373-1382, (1996)

Correlations between 5-hydroxytryptamine (5-HT) receptor binding affinities and human hallucinogenic potency have suggested that 5-HT2 receptors mediate the hallucinogenic effects of lysergic acid diethylamide (LSD) and phenethylamine hallucinogens. Electroph...

Effect of the selective 5-HT receptor agonists 8-OHDPAT and DOI on behavior and brain biogenic amines of rats.

Gen. Pharmacol. 28 , 583-587, (1997)

1. The behavioral responses, as well as the biogenic amines and metabolite contents in discrete brain areas were determined in male rats subcutaneously treated with a 5-HT1A (8-OHDPAT) or 5-HT2A (DOI) agonist at doses (0.5-2 mg/kg) sufficient to produce the t...

DOI, a 5-HT2A/2C receptor agonist, potentiates amphetamine-induced dopamine release in rat striatum.

Brain Res. 698 , 204-208, (1995)

The effects of (+-)-DOI (1-(2,5-dimethoxy-4-iodophenyl)-aminopropane) hydrochloride, a mixed 5-HT2A/2C receptor agonist, on the release of dopamine (DA) following D-amphetamine sulfate (AMP) or a DA D2 autoreceptor selective dose of (-)-apomorphine hydrochlor...