人参皂苷Rd
人参皂苷Rd结构式
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常用名 | 人参皂苷Rd | 英文名 | ginsenoside Rd |
|---|---|---|---|---|
| CAS号 | 52705-93-8 | 分子量 | 947.154 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 1015.6±65.0 °C at 760 mmHg | |
| 分子式 | C48H82O18 | 熔点 | 207 °C(dec.) | |
| MSDS | 中文版 美版 | 闪点 | 568.0±34.3 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Transcriptome analysis of Panax vietnamensis var. fuscidicus discovers putative ocotillol-type ginsenosides biosynthesis genes and genetic markers.
BMC Genomics 16 , 159, (2015) P. vietnamensis var. fuscidiscus, called "Yesanqi" in Chinese, is a new variety of P. vietnamensis, which was first found in Jinping County, the southern part of Yunnan Province, China. Compared with other Panax plants, this species contains higher content of... |
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Protective effects of ginsenoside Rd on PC12 cells against hydrogen peroxide.
Biol. Pharm. Bull. 31(10) , 1923-7, (2008) Oxidative stress-induced cell damage has been implicated in a variety of neurodegenerative disorders. In the current study, we investigated the protective role of ginsenoside Rd against the cytotoxicity induced by exposure to hydrogen peroxide (H(2)O(2)) and ... |
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Bioconversion of ginsenoside Rc into Rd by a novel α-L-arabinofuranosidase, Abf22-3 from Leuconostoc sp. 22-3: cloning, expression, and enzyme characterization.
Antonie van Leeuwenhoek 103(4) , 747-54, (2013) A novel α-L-arabinofuranosidase (Abf22-3) that could biotransform ginsenoside Rc into Rd was obtained from the ginsenoside converting Leuconostoc sp. strain 22-3, isolated from the Korean fermented food kimchi. The gene, termed abf22-3, consisting of 1,527 bp... |
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Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats.
Neurochem. Int. 58(3) , 391-8, (2011) We previously found that ginsenoside Rd (Rd), one of the main active ingredients in Panax ginseng, attenuates neuronal oxidative damage in vitro induced by hydrogen peroxide and oxygen-glucose deprivation. In this study, we sought to investigate the potential... |
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Highly selective microbial transformation of major ginsenoside Rb1 to gypenoside LXXV by Esteya vermicola CNU120806.
J. Appl. Microbiol. 113(4) , 807-14, (2012) This study examined the biotransformation pathway of ginsenoside Rb(1) by the fungus Esteya vermicola CNU 120806.Ginsenosides Rb(1) and Rd were extracted from the root of Panax ginseng. Liquid fermentation and purified enzyme hydrolysis were employed to inves... |
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Pharmacokinetic, tissue distribution and excretion of ginsenoside-Rd in rodents.
Phytomedicine 19(3-4) , 369-73, (2012) Ginsenoside-Rd (GS-Rd) is one of the major active components of Panax ginseng, and was shown to have the protective effects against several insults. However, we still lack some basic knowledge of GS-Rd, including its pharmacokinetic, tissue distribution and e... |
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Ginsenoside Rd stimulates the differentiation and mineralization of osteoblastic MC3T3-E1 cells by activating AMP-activated protein kinase via the BMP-2 signaling pathway.
Fitoterapia 83(1) , 215-22, (2012) As part of our search for biologically active anti-osteoporotic agents that enhance the differentiation and mineralization of osteoblastic MC3T3-E1 cells, we identified the ginsenoside Rd as the most active compound among ginsenosides. In this study, we showe... |
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Ginsennoside rd attenuates cognitive dysfunction in a rat model of Alzheimer's disease.
Neurochem. Res. 37(12) , 2738-47, (2012) Alzheimer's disease is a neurodegenerative disease characterized by the production of β-amyloid proteins and hyperphosphorylation of tau protein. Inflammation and apoptotic severity were highly correlated with earlier age at onset of Alzheimer's disease and w... |
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Ginsenoside Rd protects neurons against glutamate-induced excitotoxicity by inhibiting ca(2+) influx.
Cell. Mol. Neurobiol. 32(1) , 121-8, (2012) Our previous studies have demonstrated that ginsenoside Rd (GSRd), one of the principal ingredients of Pana notoginseng, has neuroprotective effects against ischemic stroke. However, the possible mechanism(s) underlying the neuroprotection of GSRd is/are stil... |
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Inhibitory effect of ginsenoside-Rd on carrageenan-induced inflammation in rats.
Can. J. Physiol. Pharmacol. 90(2) , 229-36, (2012) A previous study reported that ginsenoside-Rd reduced the production of tumor necrosis factor-α by inhibiting nuclear factor-κB in lipopolysaccharide-activated N9 microglia in vitro. The aim of the present study was to confirm the anti-inflammatory effects an... |