2-噻吩乙酰氯
2-噻吩乙酰氯结构式
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常用名 | 2-噻吩乙酰氯 | 英文名 | 2-Thiopheneacetyl chloride |
|---|---|---|---|---|
| CAS号 | 39098-97-0 | 分子量 | 160.621 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 202.4±0.0 °C at 760 mmHg | |
| 分子式 | C6H5ClOS | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 88.7±22.6 °C | |
| 符号 |
GHS05, GHS07 |
信号词 | Danger |
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Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.
Bioorg. Med. Chem. 22(17) , 4968-97, (2014) TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led to an indazole core with key sulfamoylphenyl and acetamido m... |
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Design and synthesis of a beta-lactamase activated 5-fluorouracil prodrug.
Bioorg. Med. Chem. Lett. 19(4) , 1261-3, (2009) An efficient synthesis of a 5-fluorouracil-cephalosporin prodrug is described for use against colorectal and other cancers in antibody and gene-directed therapies. The compound shows stability in aqueous media until specifically activated by beta-lactamase (b... |
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Synthesis and biological evaluation of some 6-arylamidomorphines as analogues of morphine-6-glucuronide.
Bioorg. Med. Chem. 12(22) , 5983-90, (2004) A series of 6-beta-arylamidomorphines was synthesized and biologically evaluated. Various aryl substituents were introduced into the arylamidomorphines to examine substituent structure-activity relationships. Competition binding assays showed that compounds 1... |
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Development of an efficient synthesis for a nipecotate-containing immunopotentiator. Moher ED, et al.
Org. Process Res. Dev. 8(4) , 593-6, (2004)
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Synthesis and Biological Evaluation of N, N'-di (thiopheneacetyl) diamines Series as Antitubercular Agents. Nora de Souza MV, et al.
Phosphorus. Sulfur. Silicon Relat. Elem. 183(12) , 2990-7, (2008)
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