2-Thiopheneacetyl chloride
2-Thiopheneacetyl chloride structure
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Common Name | 2-Thiopheneacetyl chloride | ||
|---|---|---|---|---|
| CAS Number | 39098-97-0 | Molecular Weight | 160.621 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 202.4±0.0 °C at 760 mmHg | |
| Molecular Formula | C6H5ClOS | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 88.7±22.6 °C | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.
Bioorg. Med. Chem. 22(17) , 4968-97, (2014) TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led to an indazole core with key sulfamoylphenyl and acetamido m... |
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Design and synthesis of a beta-lactamase activated 5-fluorouracil prodrug.
Bioorg. Med. Chem. Lett. 19(4) , 1261-3, (2009) An efficient synthesis of a 5-fluorouracil-cephalosporin prodrug is described for use against colorectal and other cancers in antibody and gene-directed therapies. The compound shows stability in aqueous media until specifically activated by beta-lactamase (b... |
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Bioorg. Med. Chem. 12(22) , 5983-90, (2004) A series of 6-beta-arylamidomorphines was synthesized and biologically evaluated. Various aryl substituents were introduced into the arylamidomorphines to examine substituent structure-activity relationships. Competition binding assays showed that compounds 1... |
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Org. Process Res. Dev. 8(4) , 593-6, (2004)
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Synthesis and Biological Evaluation of N, N'-di (thiopheneacetyl) diamines Series as Antitubercular Agents. Nora de Souza MV, et al.
Phosphorus. Sulfur. Silicon Relat. Elem. 183(12) , 2990-7, (2008)
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