2-氨基-N-(喹啉-8-基)苯磺酰胺
2-氨基-N-(喹啉-8-基)苯磺酰胺结构式
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常用名 | 2-氨基-N-(喹啉-8-基)苯磺酰胺 | 英文名 | QBS |
|---|---|---|---|---|
| CAS号 | 16082-64-7 | 分子量 | 299.35 | |
| 密度 | 1.437g/cm3 | 沸点 | 540.7ºC at 760 mmHg | |
| 分子式 | C15H13N3O2S | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 280.8ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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G2 arrest and apoptosis by 2-amino-N-quinoline-8-yl-benzenesulfonamide (QBS), a novel cytotoxic compound.
Biochem. Pharmacol. 69 , 1333-1341, (2005) We screened a library of 11,000 small molecular weight chemicals, looking for compounds that affect cell viability. We have identified 2-amino-N-quinoline-8-yl-benzenesulfonamide (QBS) as a potent cytotoxic compound that induces cell cycle arrest and apoptosi... |
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ADAM-mediated amphiregulin shedding and EGFR transactivation.
Cell Prolif. 42 , 799-812, (2009) The ectodomain shedding of epidermal growth factor receptor (EGFR) ligands, such as amphiregulin (AREG), by ADAMs (A Disintegrin And Metalloproteases) can be stimulated by G protein-coupled receptor (GPCR) agonists. Interactions between the CXCR4 GPCR and the... |
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