QBS
QBS structure
|
Common Name | QBS | ||
|---|---|---|---|---|
| CAS Number | 16082-64-7 | Molecular Weight | 299.35 | |
| Density | 1.437g/cm3 | Boiling Point | 540.7ºC at 760 mmHg | |
| Molecular Formula | C15H13N3O2S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 280.8ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of QBSNUN82647 inhibits cell cycle at G2 phase and induces apoptosis[1]. |
| Name | 2-amino-N-quinolin-8-ylbenzenesulfonamide |
|---|---|
| Synonym | More Synonyms |
| Description | NUN82647 inhibits cell cycle at G2 phase and induces apoptosis[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.437g/cm3 |
|---|---|
| Boiling Point | 540.7ºC at 760 mmHg |
| Molecular Formula | C15H13N3O2S |
| Molecular Weight | 299.35 |
| Flash Point | 280.8ºC |
| Exact Mass | 299.07300 |
| PSA | 93.46000 |
| LogP | 4.35280 |
| Vapour Pressure | 9.36E-12mmHg at 25°C |
| Index of Refraction | 1.727 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| RIDADR | NONH for all modes of transport |
| HS Code | 2935009090 |
|
~92%
QBS CAS#:16082-64-7 |
| Literature: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK; LANDRY, Donald, W.; KIM, Tae-Wan; DENG, Shi-Xian; GONG, Gangli; HWANG, Jeremy, C.; XIE, Yuli; LIU, Yidong; RINDERSPACHER, Alison Patent: WO2010/51064 A1, 2010 ; Location in patent: Page/Page column 5; 34 ; WO 2010/051064 A1 |
|
~%
QBS CAS#:16082-64-7 |
| Literature: VIFOR (INTERNATIONAL) AG Patent: US2012/214803 A1, 2012 ; US 20120214803 A1 |
|
~%
QBS CAS#:16082-64-7 |
| Literature: VIFOR (INTERNATIONAL) AG Patent: US2012/214803 A1, 2012 ; US 20120214803 A1 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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G2 arrest and apoptosis by 2-amino-N-quinoline-8-yl-benzenesulfonamide (QBS), a novel cytotoxic compound.
Biochem. Pharmacol. 69 , 1333-1341, (2005) We screened a library of 11,000 small molecular weight chemicals, looking for compounds that affect cell viability. We have identified 2-amino-N-quinoline-8-yl-benzenesulfonamide (QBS) as a potent cyt... |
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ADAM-mediated amphiregulin shedding and EGFR transactivation.
Cell Prolif. 42 , 799-812, (2009) The ectodomain shedding of epidermal growth factor receptor (EGFR) ligands, such as amphiregulin (AREG), by ADAMs (A Disintegrin And Metalloproteases) can be stimulated by G protein-coupled receptor (... |
| AmbscL35/057 |
| 2-AMINO-N-QUINOLINE-8-YLBENZENESULFONAMIDE |
| N-(quinolin-8-yl)-2-amino-benzenesulfonamide |
| 8-(2-Aminophenylsulfonylamino)chinolin |
| QBS |
| 2-Amino-N-quinolin-8-yl-benzenesulfonamide |