QBS
QBS structure
|
Common Name | QBS | ||
|---|---|---|---|---|
| CAS Number | 16082-64-7 | Molecular Weight | 299.35 | |
| Density | 1.437g/cm3 | Boiling Point | 540.7ºC at 760 mmHg | |
| Molecular Formula | C15H13N3O2S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 280.8ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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G2 arrest and apoptosis by 2-amino-N-quinoline-8-yl-benzenesulfonamide (QBS), a novel cytotoxic compound.
Biochem. Pharmacol. 69 , 1333-1341, (2005) We screened a library of 11,000 small molecular weight chemicals, looking for compounds that affect cell viability. We have identified 2-amino-N-quinoline-8-yl-benzenesulfonamide (QBS) as a potent cytotoxic compound that induces cell cycle arrest and apoptosi... |
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ADAM-mediated amphiregulin shedding and EGFR transactivation.
Cell Prolif. 42 , 799-812, (2009) The ectodomain shedding of epidermal growth factor receptor (EGFR) ligands, such as amphiregulin (AREG), by ADAMs (A Disintegrin And Metalloproteases) can be stimulated by G protein-coupled receptor (GPCR) agonists. Interactions between the CXCR4 GPCR and the... |
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