bis(7)-Tacrine
bis(7)-Tacrine结构式
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常用名 | bis(7)-Tacrine | 英文名 | BIS(7)-TACRINE |
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| CAS号 | 224445-12-9 | 分子量 | 565.619 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C33H42Cl2N4 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | N/A |
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Synthesis of alkylene linked bis-THA and linked benzyl-THA as highly potent and selective inhibitors and molecular probes of acetylcholinesterase. Pang, et al.
J. Chem. Soc. Perkin Trans. I , 171, (1997)
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Highly potent, selective, and low cost bis-tetrahydroaminacrine inhibitors of acetylcholinesterase. Steps toward novel drugs for treating Alzheimer's disease.
J. Biol. Chem. 271 , 23646, (1996) We report highly potent, selective, and low cost bifunctional acetylcholinesterase (AChE) inhibitors developed by our two-step prototype optimization strategy utilizing computer modeling of ligand docking with target proteins: 1) identify low affinity sites n... |
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