NQTrp
NQTrp结构式
|
常用名 | NQTrp | 英文名 | NQTrp |
|---|---|---|---|---|
| CAS号 | 185351-19-3 | 分子量 | 360.36300 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C21H16N2O4 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Combined experimental and simulation studies suggest a revised mode of action of the anti-Alzheimer disease drug NQ-Trp.
Chemistry 21 , 12657-66, (2015) Inhibition of the aggregation of the monomeric peptide β-amyloid (Aβ) into oligomers is a widely studied therapeutic approach in Alzheimer's disease (AD). Many small molecules have been reported to work in this way, including 1,4-naphthoquinon-2-yl-L-tryptoph... |
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Naphthoquinone-Tryptophan Hybrid Inhibits Aggregation of the Tau-Derived Peptide PHF6 and Reduces Neurotoxicity.
J. Alzheimers Dis. 51 , 165-78, (2016) Tauopathies, such as Alzheimer's disease (AD), are a group of disorders characterized neuropathologically by intracellular toxic accumulations of abnormal protein aggregates formed by misfolding of the microtubule-associated protein tau. Since protein self-as... |
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