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4,4,4-三氟丁酸乙酯

4,4,4-三氟丁酸乙酯结构式
4,4,4-三氟丁酸乙酯结构式
品牌特惠专场
常用名 4,4,4-三氟丁酸乙酯 英文名 Ethyl 4,4,4-Trifluorobutyrate
CAS号 371-26-6 分子量 170.13000
密度 1.16 g/mL at 25 °C(lit.) 沸点 127 °C(lit.)
分子式 C6H9F3O2 熔点 N/A
MSDS 中文版 美版 闪点 92 °F
符号 GHS02 GHS07
GHS02, GHS07
信号词 Warning

Compounds Derived from 3-Halo-1, 1, 1-trifluoropropane1, 2. McBee E, et al.

J. Am. Chem. Soc. 72(11) , 5071-73, (1950)

J. Org. Chem. 60 , 5434, (1995)

Synthesis, structure-activity relationships, and pharmacological evaluation of a series of fluorinated 3-benzyl-5-indolecarboxamides: identification of 4-[[5-[((2R)-2-methyl-4,4,4-trifluorobutyl)carbamoyl]-1-methyl indol- 3-yl]methyl]-3-methoxy-N-[(2-methylphenyl)sulfonyl]benzamide, a potent, orally active antagonist of leukotrienes D4 and E4.

J. Med. Chem. 37 , 1282, (1994)

The continued exploration of a series of 3-(arylmethyl)-1H-indole-5-carboxamides by the introduction of fluorinated amide substituents has resulted in the discovery of 4-[[5-[((2R)-2-methyl-4,4,4-trifluorobutyl)carbamoyl]-1-methyli ndol- 3-yl]methyl]-3-methox...