Ethyl 4,4,4-Trifluorobutyrate
Ethyl 4,4,4-Trifluorobutyrate structure
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Common Name | Ethyl 4,4,4-Trifluorobutyrate | ||
|---|---|---|---|---|
| CAS Number | 371-26-6 | Molecular Weight | 170.13000 | |
| Density | 1.16 g/mL at 25 °C(lit.) | Boiling Point | 127 °C(lit.) | |
| Molecular Formula | C6H9F3O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 92 °F | |
| Symbol |
GHS02, GHS07 |
Signal Word | Warning | |
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Compounds Derived from 3-Halo-1, 1, 1-trifluoropropane1, 2. McBee E, et al.
J. Am. Chem. Soc. 72(11) , 5071-73, (1950)
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J. Org. Chem. 60 , 5434, (1995)
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Synthesis, structure-activity relationships, and pharmacological evaluation of a series of fluorinated 3-benzyl-5-indolecarboxamides: identification of 4-[[5-[((2R)-2-methyl-4,4,4-trifluorobutyl)carbamoyl]-1-methyl indol- 3-yl]methyl]-3-methoxy-N-[(2-methylphenyl)sulfonyl]benzamide, a potent, orally active antagonist of leukotrienes D4 and E4.
J. Med. Chem. 37 , 1282, (1994) The continued exploration of a series of 3-(arylmethyl)-1H-indole-5-carboxamides by the introduction of fluorinated amide substituents has resulted in the discovery of 4-[[5-[((2R)-2-methyl-4,4,4-trifluorobutyl)carbamoyl]-1-methyli ndol- 3-yl]methyl]-3-methox... |
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