Ethyl 4,4,4-Trifluorobutyrate

Modify Date: 2025-09-10 15:38:15

Ethyl 4,4,4-Trifluorobutyrate structure	Common Name	Ethyl 4,4,4-Trifluorobutyrate
	CAS Number	371-26-6	Molecular Weight	170.13000
	Density	1.16 g/mL at 25 °C(lit.)	Boiling Point	127 °C(lit.)
	Molecular Formula	C₆H₉F₃O₂	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	92 °F
	Symbol	GHS02, GHS07	Signal Word	Warning

Name	Ethyl 4,4,4-Trifluorobutyrate
Synonym	More Synonyms

Density	1.16 g/mL at 25 °C(lit.)
Boiling Point	127 °C(lit.)
Molecular Formula	C₆H₉F₃O₂
Molecular Weight	170.13000
Flash Point	92 °F
Exact Mass	170.05500
PSA	26.30000
LogP	1.89200
Index of Refraction	n20/D 1.3516(lit.)
Storage condition	Flammables area

Ethyl 4,4,4-Trifluorobutyrate MSDS(Chinese)

Symbol	GHS02, GHS07
Signal Word	Warning
Hazard Statements	H226-H302-H312-H319-H332-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful;
Risk Phrases	R10;R20/21/22;R36/37
Safety Phrases	S16-S26-S36
RIDADR	UN 3272 3/PG 3
WGK Germany	3
Packaging Group	III
Hazard Class	3
HS Code	2915900090

Precursor 10
CAS#:25597-16-4 Ethyl-(2E)-4,4,... CAS#:460-37-7 1,1,1-Trifluoro... CAS#:64-17-5 Ethanol CAS#:201230-82-2 carbon monoxide
CAS#:769169-70-2 4,4,4-trifluoro... CAS#:75-90-1 fluoral CAS#:2707-65-5 3-acetoxy-4,4,4... CAS#:372-30-5 Ethyl 3-hydroxy...
CAS#:1522-43-6 ethyl 3-oxo-4,4... CAS#:541-41-3 Ethyl chloroformate
DownStream 6
CAS#:406-87-1 4,4,4-Trifluoro... CAS#:406-93-9 4,4,4-Trifluoro... CAS#:461-18-7 4,4,4-Trifluoro... CAS#:143484-00-8 Ethyl 4,4,4-tri...
CAS#:885275-92-3 ETHYL 2,2-DIMET... CAS#:406-91-7 4,4,4-Trifluoro...

HS Code	2915900090
Summary	2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Compounds Derived from 3-Halo-1, 1, 1-trifluoropropane1, 2. McBee E, et al.

J. Am. Chem. Soc. 72(11) , 5071-73, (1950)

J. Org. Chem. 60 , 5434, (1995)

Synthesis, structure-activity relationships, and pharmacological evaluation of a series of fluorinated 3-benzyl-5-indolecarboxamides: identification of 4-[[5-[((2R)-2-methyl-4,4,4-trifluorobutyl)carbamoyl]-1-methyl indol- 3-yl]methyl]-3-methoxy-N-[(2-methylphenyl)sulfonyl]benzamide, a potent, orally active antagonist of leukotrienes D4 and E4.

J. Med. Chem. 37 , 1282, (1994)

The continued exploration of a series of 3-(arylmethyl)-1H-indole-5-carboxamides by the introduction of fluorinated amide substituents has resulted in the discovery of 4-[[5-[((2R)-2-methyl-4,4,4-trif...

ethyl 4,4,4-trifluorobutanoate

MFCD00041398

4,4,4-Trifluorobutyric Acid Ethyl Ester

Ethyl 4,4,4-trifluorobutyrate