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4-羟基-7-三氟甲基-3-喹啉羧酸

4-羟基-7-三氟甲基-3-喹啉羧酸结构式
4-羟基-7-三氟甲基-3-喹啉羧酸结构式
品牌特惠专场
常用名 4-羟基-7-三氟甲基-3-喹啉羧酸 英文名 4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid
CAS号 574-92-5 分子量 257.16500
密度 1.55 g/cm3 沸点 354.7ºC at 760 mmHg
分子式 C11H6F3NO3 熔点 259-260 °C (dec.)(lit.)
MSDS 中文版 美版 闪点 168.3ºC
符号 GHS07
GHS07
信号词 Warning

Synthesis and testing of new antileukemic Schiff bases of N-hydroxy-N'-aminoguanidine against CCRF-CEM/0 human leukemia cells in vitro and synergism studies with cytarabine (Ara-C).

Pharm. Res. 10(4) , 515-20, (1993)

A series of eight new N-hydroxy-N'-aminoguanidine (HAG) Schiff bases [ArCH = NNHC(= NH)NHOH.tosylate] was synthesized as potential antitumor agents through the inhibition of the enzyme ribonucleotide reductase (EC 1.17.4.1). Five of the HAG derivatives (LK02 ...