4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid
4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid structure
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Common Name | 4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid | ||
|---|---|---|---|---|
| CAS Number | 574-92-5 | Molecular Weight | 257.16500 | |
| Density | 1.55 g/cm3 | Boiling Point | 354.7ºC at 760 mmHg | |
| Molecular Formula | C11H6F3NO3 | Melting Point | 259-260 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 168.3ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Synthesis and testing of new antileukemic Schiff bases of N-hydroxy-N'-aminoguanidine against CCRF-CEM/0 human leukemia cells in vitro and synergism studies with cytarabine (Ara-C).
Pharm. Res. 10(4) , 515-20, (1993) A series of eight new N-hydroxy-N'-aminoguanidine (HAG) Schiff bases [ArCH = NNHC(= NH)NHOH.tosylate] was synthesized as potential antitumor agents through the inhibition of the enzyme ribonucleotide reductase (EC 1.17.4.1). Five of the HAG derivatives (LK02 ... |
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