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10-Oxo Morphine

10-Oxo Morphine结构式
10-Oxo Morphine结构式
品牌特惠专场
常用名 10-Oxo Morphine 英文名 10-Oxo Morphine
CAS号 68254-48-8 分子量 299.32100
密度 1.53g/cm3 沸点 557ºC at 760 mmHg
分子式 C17H17NO4 熔点 N/A
MSDS N/A 闪点 290.6ºC
符号 GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
信号词 Danger

Impurities in a morphine sulfate drug product identified as 5-(hydroxymethyl)-2-furfural, 10-hydroxymorphine and 10-oxomorphine.

J. Pharm. Sci. 92(3) , 485-93, (2003)

Stability testing of morphine sulfate formulated with nonpareil sugar seeds (consisting of sucrose and starch) and fumaric acid revealed the formation of the three impurities 5-(hydroxymethyl)-2-furfural, 10-hydroxymorphine and 10-oxomorphine. 5-(Hydroxymethy...

Synthesis and determination of 10-oxomorphine, a decomposition product of morphine.

Pharmazie 39(10) , 687-8, (1984)

10-Oxomorphine, a decomposition product of morphine, was synthesized from 6-O-acetylcodeine, which was oxidized with chromic acid to 6-O-acetyl-10-hydroxycodeine. This substance was then oxidized with manganese dioxide to 6-O-acetyl-10-oxocodeine, which on hy...