Flt-3抑制剂
Flt-3抑制剂结构式
|
常用名 | Flt-3抑制剂 | 英文名 | TCS 359 |
|---|---|---|---|---|
| CAS号 | 301305-73-7 | 分子量 | 360.427 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 454.4±45.0 °C at 760 mmHg | |
| 分子式 | C18H20N2O4S | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 228.6±28.7 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3.
Bioorg. Med. Chem. Lett. 16 , 3282-3286 A series of 2-acylaminothiophene-3-carboxamides has been identified which exhibit potent inhibitory activity against the FLT3 tyrosine kinase. Compound 44 inhibits the isolated enzyme (IC50 = 0.027 microM) and blocks the proliferation of MV4-11 cells (IC50 = ... |
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