TCS 359
TCS 359 structure
|
Common Name | TCS 359 | ||
|---|---|---|---|---|
| CAS Number | 301305-73-7 | Molecular Weight | 360.427 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 454.4±45.0 °C at 760 mmHg | |
| Molecular Formula | C18H20N2O4S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 228.6±28.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3.
Bioorg. Med. Chem. Lett. 16 , 3282-3286 A series of 2-acylaminothiophene-3-carboxamides has been identified which exhibit potent inhibitory activity against the FLT3 tyrosine kinase. Compound 44 inhibits the isolated enzyme (IC50 = 0.027 microM) and blocks the proliferation of MV4-11 cells (IC50 = ... |
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