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3-氟-4-溴甲苯

3-氟-4-溴甲苯结构式
3-氟-4-溴甲苯结构式
品牌特惠专场
常用名 3-氟-4-溴甲苯 英文名 4-Bromo-3-fluorotoluene
CAS号 452-74-4 分子量 189.025
密度 1.5±0.1 g/cm3 沸点 185.7±20.0 °C at 760 mmHg
分子式 C7H6BrF 熔点 N/A
MSDS 中文版 美版 闪点 68.6±16.6 °C
符号 GHS02 GHS07
GHS02, GHS07
信号词 Warning

Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates.

J. Med. Chem. 54 , 2293-306, (2011)

Poor blood-brain barrier penetration of nonsteroidal anti-inflammatory drugs (NSAIDs) has been blamed for the failure of the selective amyloid lowering agent (SALA) R-flurbiprofen in phase 3 clinical trials for Alzheimer's disease (AD). NO-donor NSAIDs (NO-NS...

Aryloxy substituted N-arylpiperazinones as dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I.

Bioorg. Med. Chem. Lett. 11(11) , 1411-5, (2001)

A series of aryloxy substituted piperazinones with dual farnesyltransferase/geranylgeranyltransferase-I inhibitory activity was prepared. These compounds were found to have potent inhibitory activity in vitro and are promising agents for the inhibition of Ki-...

Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion.

J. Med. Chem. 48 , 5705-20, (2005)

Flurbiprofen, a nonsteroidal antiinflammatory drug (NSAID), has been recently described to selectively inhibit beta-amyloid(1)(-)(42) (Abeta42) secretion, the most toxic component of the senile plaques present in the brain of Alzheimer patients. The use of th...

SYNTHESIS OF 4-CHLORO-3-FLUOROTOLUENE AND 4-BROMO-3-FLUOROTOLUENE [J]. Tao ZHXXJ.

Speciality Petrochemicals 1 , 014, (2007)

Yaws CL.

The Yaws Handbook of Physical Properties for Hydrocarbons and Chemicals 2nd ed.,, (2015), 91