4-Bromo-3-fluorotoluene

Modify Date: 2025-08-20 20:24:16

4-Bromo-3-fluorotoluene Structure
4-Bromo-3-fluorotoluene structure
Common Name 4-Bromo-3-fluorotoluene
CAS Number 452-74-4 Molecular Weight 189.025
Density 1.5±0.1 g/cm3 Boiling Point 185.7±20.0 °C at 760 mmHg
Molecular Formula C7H6BrF Melting Point N/A
MSDS Chinese USA Flash Point 68.6±16.6 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning

 Names

Name 4-Bromo-3-fluorotoluene
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 185.7±20.0 °C at 760 mmHg
Molecular Formula C7H6BrF
Molecular Weight 189.025
Flash Point 68.6±16.6 °C
Exact Mass 187.963684
LogP 3.41
Vapour Pressure 0.9±0.3 mmHg at 25°C
Index of Refraction 1.527
Storage condition Flammables area

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning
Hazard Statements H226-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R10;R36/37/38
Safety Phrases S26-S37/39-S16
RIDADR UN 1993 3/PG 3
WGK Germany 3
Packaging Group III
Hazard Class 3
HS Code 2903999090

 Synthetic Route

~58%

4-Bromo-3-fluorotoluene Structure

4-Bromo-3-fluor...

CAS#:452-74-4

Literature: Zou, Xinzhuo; Qiu, Zongxing Journal of Fluorine Chemistry, 2002 , vol. 116, # 2 p. 173 - 179

~%

4-Bromo-3-fluorotoluene Structure

4-Bromo-3-fluor...

CAS#:452-74-4

Literature: Zou, Xinzhuo; Qiu, Zongxing Journal of Fluorine Chemistry, 2002 , vol. 116, # 2 p. 173 - 179

~%

4-Bromo-3-fluorotoluene Structure

4-Bromo-3-fluor...

CAS#:452-74-4

Literature: Zou, Xinzhuo; Qiu, Zongxing Journal of Fluorine Chemistry, 2002 , vol. 116, # 2 p. 173 - 179

~%

4-Bromo-3-fluorotoluene Structure

4-Bromo-3-fluor...

CAS#:452-74-4

Literature: Wittig,G.; Matzura,H. Justus Liebigs Annalen der Chemie, 1970 , vol. 732, p. 97 - 106

~%

4-Bromo-3-fluorotoluene Structure

4-Bromo-3-fluor...

CAS#:452-74-4

Literature: Varma; Raman; Nilkantiah Journal of the Indian Chemical Society, 1944 , vol. 21, p. 112,114

~%

4-Bromo-3-fluorotoluene Structure

4-Bromo-3-fluor...

CAS#:452-74-4

Literature: Varma; Raman; Nilkantiah Journal of the Indian Chemical Society, 1944 , vol. 21, p. 112,114

~%

Detail
Literature: Varma; Raman; Nilkantiah Journal of the Indian Chemical Society, 1944 , vol. 21, p. 112,114

 Customs

HS Code 2903999090
Summary 2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Articles5

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Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates.

J. Med. Chem. 54 , 2293-306, (2011)

Poor blood-brain barrier penetration of nonsteroidal anti-inflammatory drugs (NSAIDs) has been blamed for the failure of the selective amyloid lowering agent (SALA) R-flurbiprofen in phase 3 clinical ...

Aryloxy substituted N-arylpiperazinones as dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I.

Bioorg. Med. Chem. Lett. 11(11) , 1411-5, (2001)

A series of aryloxy substituted piperazinones with dual farnesyltransferase/geranylgeranyltransferase-I inhibitory activity was prepared. These compounds were found to have potent inhibitory activity ...

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 Synonyms

4-bromo-3-fluoro-toluene
Benzene, 1-bromo-2-fluoro-4-methyl-
1-Bromo-2-fluoro-4-methylbenzene
4-BroMo-3-fluorotoluene 5GR
3-Fluoro-4-bromo-toluone
4-Bromo-3-fluorotoluene
4-Bromo-3-fluoro-1-methylbenzene
1-Bromo-2-fluoro-4-methyl-benzene
4-Brom-3-fluor-toluol
2-fluoro-4-methylbromobenzene
3-FLUORO-4-BROMO-TOLUENE
4-Bromo-3-flurotoluene
MFCD00040940
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