4-Bromo-3-fluorotoluene
4-Bromo-3-fluorotoluene structure
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Common Name | 4-Bromo-3-fluorotoluene | ||
|---|---|---|---|---|
| CAS Number | 452-74-4 | Molecular Weight | 189.025 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 185.7±20.0 °C at 760 mmHg | |
| Molecular Formula | C7H6BrF | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 68.6±16.6 °C | |
| Symbol |
GHS02, GHS07 |
Signal Word | Warning | |
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Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates.
J. Med. Chem. 54 , 2293-306, (2011) Poor blood-brain barrier penetration of nonsteroidal anti-inflammatory drugs (NSAIDs) has been blamed for the failure of the selective amyloid lowering agent (SALA) R-flurbiprofen in phase 3 clinical trials for Alzheimer's disease (AD). NO-donor NSAIDs (NO-NS... |
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Aryloxy substituted N-arylpiperazinones as dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I.
Bioorg. Med. Chem. Lett. 11(11) , 1411-5, (2001) A series of aryloxy substituted piperazinones with dual farnesyltransferase/geranylgeranyltransferase-I inhibitory activity was prepared. These compounds were found to have potent inhibitory activity in vitro and are promising agents for the inhibition of Ki-... |
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Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion.
J. Med. Chem. 48 , 5705-20, (2005) Flurbiprofen, a nonsteroidal antiinflammatory drug (NSAID), has been recently described to selectively inhibit beta-amyloid(1)(-)(42) (Abeta42) secretion, the most toxic component of the senile plaques present in the brain of Alzheimer patients. The use of th... |
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SYNTHESIS OF 4-CHLORO-3-FLUOROTOLUENE AND 4-BROMO-3-FLUOROTOLUENE [J]. Tao ZHXXJ.
Speciality Petrochemicals 1 , 014, (2007)
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Yaws CL.
The Yaws Handbook of Physical Properties for Hydrocarbons and Chemicals 2nd ed.,, (2015), 91
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