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二-2-吡啶酮-4-环己基-4-甲基-3-氨基硫脲

二-2-吡啶酮-4-环己基-4-甲基-3-氨基硫脲结构式
二-2-吡啶酮-4-环己基-4-甲基-3-氨基硫脲结构式
品牌特惠专场
常用名 二-2-吡啶酮-4-环己基-4-甲基-3-氨基硫脲 英文名 DpC
CAS号 1382469-39-7 分子量 353.48
密度 1.2±0.1 g/cm3 沸点 510.7±48.0 °C at 760 mmHg
分子式 C19H23N5S 熔点 N/A
MSDS 美版 闪点 262.7±29.6 °C
符号 GHS06
GHS06
信号词 Danger

The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1.

Oncotarget 6 , 8851-74, (2015)

N-myc downstream regulated gene-1 (NDRG1) is a potent metastasis suppressor that plays a key role in regulating signaling pathways involved in mediating cancer cell invasion and migration, including those derived from prostate, colon, etc. However, the mechan...

The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways.

J. Biol. Chem. 291 , 1029-52, (2016)

N-MYC downstream-regulated gene-1 (NDRG1) is a potent growth and metastasis suppressor that acts through its inhibitory effects on a wide variety of cellular signaling pathways, including the TGF-β pathway, protein kinase B (AKT)/PI3K pathway, RAS, etc. To in...